SNU-1066Homo sapiens (Human)Cancer cell line

Also known as: SNU1066

AI Summary

No AI-generated summary available for this cell line.

Basic Information

Database IDCVCL_5005
SpeciesHomo sapiens (Human)
Tissue SourceLarynx[UBERON:UBERON_0001737]

Donor Information

Age62
Age CategoryAdult
SexMale
Raceasian

Disease Information

DiseaseSquamous cell carcinoma of the larynx
LineageHead and Neck
SubtypeLarynx Squamous Cell Carcinoma
OncoTree CodeLXSC

DepMap Information

Source TypeKCLB
Source IDACH-000682_source

Known Sequence Variations

TypeGene/ProteinDescriptionZygosityNoteSource
MutationSimpleTP53c.514_559del46Homozygous-Unknown, PubMed=10369293
MutationSimpleTERTc.1-146C>T (c.250C>T) (C250T)UnspecifiedIn promoterPubMed=31068700
MutationSimpleCDKN2Ap.Asp92fs*54 (c.274delG)Homozygous-Unknown, PubMed=10369293

Haplotype Information (STR Profile)

Short Tandem Repeat (STR) profile for cell line authentication.

Amelogenin
X,Y
CSF1PO
11
D13S317
8,12
D3S1358
17
D5S818
9,11
D7S820
12
FGA
23
TH01
7,9
TPOX
8
vWA
17,18
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines

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Publications

Next-generation characterization of the Cancer Cell Line Encyclopedia.

Sellers W.R.

Nature 569:503-508(2019).

TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.

Loewer M., Sahin U., Castle J.C.

Genome Med. 7:118.1-118.7(2015).

Biology of SNU cell lines.";

Ku J.-L., Park J.-G.

Cancer Res. Treat. 37:1-19(2005).

Establishment and characterization of human laryngeal squamous cell carcinoma cell lines.

Park J.-G.

Laryngoscope 109:976-982(1999).