SNU-1196Homo sapiens (Human)Cancer cell line
Also known as: SNU1196
AI Summary
No AI-generated summary available for this cell line.
Basic Information
| Database ID | CVCL_5015 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Common hepatic duct[UBERON:UBERON_0001175] |
Donor Information
| Age Category | Unknown |
|---|---|
| Sex | Unknown |
Disease Information
| Disease | Klatskin tumor |
|---|---|
| Lineage | Biliary Tract |
| Subtype | Extrahepatic Cholangiocarcinoma |
| OncoTree Code | EHCH |
DepMap Information
| Source Type | KCLB |
|---|---|
| Source ID | ACH-000461_source |
Known Sequence Variations
| Type | Gene/Protein | Description | Zygosity | Note | Source |
|---|---|---|---|---|---|
| MutationSimple | TP53 | p.Arg273Cys (c.817C>T) | Homozygous | - | PubMed=35933914 |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Amelogenin
X
CSF1PO
10
D13S317
9
D3S1358
14,15
D5S818
11
D7S820
8,11
FGA
24,25
TH01
5,7
TPOX
10,11
vWA
14,16
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines
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Publications
Generation of a biliary tract cancer cell line atlas reveals molecular subtypes and therapeutic targets.
Vazquez F., Getz G., Bardeesy N.M.
bioRxiv 2024:07.04.601970-07.04.601970(2024).
Development and characterization of human primary cholangiocarcinoma cell lines.
Glaser S., Kennedy L., Francis H., Zhang W.-J., Alpini G.D., Ekser B.
Am. J. Pathol. 192:1200-1217(2022).
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Sellers W.R.
Nature 569:503-508(2019).
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
Cancer Res. 79:1263-1273(2019).
CG200745, an HDAC inhibitor, induces anti-tumour effects in cholangiocarcinoma cell lines via miRNAs targeting the Hippo pathway.
Jung D.E., Park S.B., Kim K., Kim C., Song S.Y.
Sci. Rep. 7:10921-10921(2017).
Isocitrate dehydrogenase mutations confer dasatinib hypersensitivity and SRC dependence in intrahepatic cholangiocarcinoma.
Bardeesy N.M.
Cancer Discov. 6:727-739(2016).
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
Loewer M., Sahin U., Castle J.C.
Genome Med. 7:118.1-118.7(2015).
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
Nature 483:603-607(2012).