SNU-1411Homo sapiens (Human)Cancer cell line

Also known as: SNU1411

AI Summary

No AI-generated summary available for this cell line.

Basic Information

Database IDCVCL_5025
SpeciesHomo sapiens (Human)
Tissue SourceRectum[UBERON:UBERON_0001052]

Donor Information

Age42
Age CategoryAdult
SexMale

Disease Information

DiseaseRectal adenocarcinoma
LineageBowel
SubtypeRectal Adenocarcinoma
OncoTree CodeREAD

DepMap Information

Source TypeKCLB
Source IDACH-002532_source

Known Sequence Variations

TypeGene/ProteinDescriptionZygosityNoteSource
MutationSimpleTP53p.Ser94Ter (c.281C>A)Homozygous-PubMed=20176655
MutationSimpleKRASp.Gly12Cys (c.34G>T)Unspecified-PubMed=21173094

Haplotype Information (STR Profile)

Short Tandem Repeat (STR) profile for cell line authentication.

Amelogenin
X
CSF1PO
10,12
D10S1248
13
D12S391
19
D13S317
10
D16S539
12,13
D18S51
14
D19S433
14
D1S1656
16,17.3
D21S11
30
D22S1045
16,17
D2S1338
19,24
D2S441
10,11
D3S1358
15
D5S818
11,13
D7S820
11
D8S1179
15
FGA
23,24
Penta D
5,12
Penta E
16,18
TH01
9
TPOX
8
vWA
20
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines

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Publications

The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets.

Linnebacher M., Cordero F., Di Nicolantonio F., Bardelli A.

Nat. Commun. 6:7002.1-7002.10(2015).

Establishment and characterization of 13 human colorectal carcinoma cell lines: mutations of genes and expressions of drug-sensitivity genes and cancer stem cell markers.

Jeon Y.-K., Kim S.-H., Kim H.-S., Park J.-H., Kim I.-J., Park J.-G.

Carcinogenesis 31:1003-1009(2010).