SNU-1460Homo sapiens (Human)Cancer cell line
Also known as: SNU1460
AI Summary
No AI-generated summary available for this cell line.
Basic Information
| Database ID | CVCL_5026 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Colon, sigmoid[UBERON:UBERON_0001159] |
Donor Information
| Age | 25 |
|---|---|
| Age Category | Adult |
| Sex | Male |
Disease Information
| Disease | Colon adenocarcinoma |
|---|---|
| Lineage | Bowel |
| Subtype | Colon Adenocarcinoma |
| OncoTree Code | COAD |
DepMap Information
| Source Type | KCLB |
|---|---|
| Source ID | ACH-002539_source |
Known Sequence Variations
| Type | Gene/Protein | Description | Zygosity | Note | Source |
|---|---|---|---|---|---|
| MutationNone reported | TP53 | - | - | - | PubMed=19787792 |
| MutationSimple | KRAS | p.Gly13Asp (c.38G>A) | Heterozygous | Somatic | from parent cell line MDA-MB-231 |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Amelogenin
X
CSF1PO
12
D10S1248
15
D12S391
17,19
D13S317
9,12
D16S539
10
D18S51
13
D19S433
13,14.2
D1S1656
16,17
D21S11
30.2,31
D22S1045
16
D2S1338
23,24
D2S441
11
D3S1358
15,17
D5S818
11
D7S820
8,11
D8S1179
13
FGA
21,23
Penta D
10,11
Penta E
13
TH01
6,7
TPOX
8,11
vWA
14,18
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines
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Publications
Identification of a novel fusion gene, FAM174A-WWC1, in early-onset colorectal cancer: establishment and characterization of four human cancer cell lines from early-onset colorectal cancers.
Ku J.-L.
Transl. Oncol. 12:1185-1195(2019).
The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets.
Linnebacher M., Cordero F., Di Nicolantonio F., Bardelli A.
Nat. Commun. 6:7002.1-7002.10(2015).