SNU-1544Homo sapiens (Human)Cancer cell line

Also known as: SNU1544

AI Summary

No AI-generated summary available for this cell line.

Basic Information

Database IDCVCL_5027
SpeciesHomo sapiens (Human)
Tissue SourceColon, ascending[UBERON:UBERON_0001156]

Donor Information

Age38
Age CategoryAdult
SexFemale

Disease Information

DiseaseColon adenocarcinoma
LineageBowel
SubtypeColon Adenocarcinoma
OncoTree CodeCOAD

DepMap Information

Source TypeKCLB
Source IDACH-001786_source

Known Sequence Variations

TypeGene/ProteinDescriptionZygosityNoteSource
MutationNone reportedTP53---PubMed=19787792
MutationSimpleMLH1p.Ser2Leu (c.5C>T)Unspecified-PubMed=20176655
MutationSimpleKRASp.Gly13Asp (c.38G>A)HeterozygousSomaticfrom parent cell line MDA-MB-231
MutationSimpleAPCp.Thr1556Asnfs*3 (c.4666dupA) (c.4666_4667insA)Heterozygous-from parent cell line WiDr

Haplotype Information (STR Profile)

Short Tandem Repeat (STR) profile for cell line authentication.

Amelogenin
X
CSF1PO
11,12
D13S317
9,11
D16S539
8,14
D18S51
12,17
D19S433
14.2,16.2
D21S11
29,30
D2S1338
19
D3S1358
15,16
D5S818
12
D7S820
11,12
D8S1179
10
FGA
20,23,24
Penta D
8,12
Penta E
9,16
TH01
7,9
TPOX
8
vWA
14,19,20,21
Gene Expression Profile
Gene expression levels and statistical distribution
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Publications

The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets.

Linnebacher M., Cordero F., Di Nicolantonio F., Bardelli A.

Nat. Commun. 6:7002.1-7002.10(2015).

Establishment and characterization of 13 human colorectal carcinoma cell lines: mutations of genes and expressions of drug-sensitivity genes and cancer stem cell markers.

Jeon Y.-K., Kim S.-H., Kim H.-S., Park J.-H., Kim I.-J., Park J.-G.

Carcinogenesis 31:1003-1009(2010).