SNU-175Homo sapiens (Human)Cancer cell line
Also known as: NCI-SNU-175, SNU175
No AI-generated summary available for this cell line.
Basic Information
| Database ID | CVCL_5031 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Peritoneum[UBERON:UBERON_0002358] |
Donor Information
| Age | 56 |
|---|---|
| Age Category | Adult |
| Sex | Female |
| Race | asian |
| Subtype Features | MSI |
Disease Information
| Disease | Colon adenocarcinoma |
|---|---|
| Lineage | Bowel |
| Subtype | Mucinous Adenocarcinoma of the Colon and Rectum |
| OncoTree Code | MACR |
DepMap Information
| Source Type | KCLB |
|---|---|
| Source ID | ACH-000989_source |
Known Sequence Variations
| Type | Gene/Protein | Description | Zygosity | Note | Source |
|---|---|---|---|---|---|
| MutationSimple | KRAS | p.Ala59Thr (c.175G>A) | Heterozygous | - | Unknown, Unknown, PubMed=10362137 |
| MutationSimple | APC | p.Gly1499Ter (c.4495G>T) | Heterozygous | - | Unknown, Unknown |
| MutationSimple | APC | p.Arg232Ter (c.694C>T) | Heterozygous | - | Unknown, Unknown |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
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Publications
Pan-cancer proteomic map of 949 human cell lines.";
Robinson P.J., Zhong Q., Garnett M.J., Reddel R.R.
Cancer Cell 40:835-849.e8(2022).
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Sellers W.R.
Nature 569:503-508(2019).
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
Cancer Res. 79:1263-1273(2019).
Genomic determinants of protein abundance variation in colorectal cancer cells.
Wessels L.F.A., Saez-Rodriguez J., McDermott U., Choudhary J.S.
Cell Rep. 20:2201-2214(2017).
A landscape of pharmacogenomic interactions in cancer.";
Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
Cell 166:740-754(2016).
The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets.
Linnebacher M., Cordero F., Di Nicolantonio F., Bardelli A.
Nat. Commun. 6:7002.1-7002.10(2015).
Colorectal cancer cell lines are representative models of the main molecular subtypes of primary cancer.
Mariadason J.M., Sieber O.M.
Cancer Res. 74:3238-3247(2014).
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
Nature 483:603-607(2012).
Mutations in hMSH6 alone are not sufficient to cause the microsatellite instability in colorectal cancer cell lines.
Ku J.-L., Yoon K.-A., Kim D.-Y., Park J.-G.
Eur. J. Cancer 35:1724-1729(1999).