SNU-201Homo sapiens (Human)Cancer cell line

Also known as: NCI-SNU-201, SNU201

AI Summary

No AI-generated summary available for this cell line.

Basic Information

Database IDCVCL_5033
SpeciesHomo sapiens (Human)
Tissue SourceBrain[UBERON:UBERON_0000955]

Donor Information

Age58
Age CategoryAdult
SexMale
Raceasian

Disease Information

DiseaseGlioblastoma
LineageCNS/Brain
SubtypeGlioblastoma
OncoTree CodeGB

DepMap Information

Source TypeKCLB
Source IDACH-000623_source

Known Sequence Variations

TypeGene/ProteinDescriptionZygosityNoteSource
MutationSimpleTP53p.Asp281Asn (c.841G>A)Heterozygous-Unknown
MutationSimpleTP53c.376-1G>A (p.Tyr126_Lys132del, c.376_396del21)UnspecifiedSplice acceptor mutationfrom parent cell line U-1285

Haplotype Information (STR Profile)

Short Tandem Repeat (STR) profile for cell line authentication.

Amelogenin
X,Y
CSF1PO
12
D13S317
11
D3S1358
15,16
D5S818
9,10
D7S820
8,11
FGA
18,25
TH01
6,8
TPOX
9
vWA
16,18
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines

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Publications

Comprehensive transcriptomic analysis of cell lines as models of primary tumors across 22 tumor types.

van 't Veer L.J., Butte A.J., Goldstein T., Sirota M.

Nat. Commun. 10:3574.1-3574.11(2019).

Next-generation characterization of the Cancer Cell Line Encyclopedia.

Sellers W.R.

Nature 569:503-508(2019).

An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.

Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.

Cancer Res. 79:1263-1273(2019).

TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.

Loewer M., Sahin U., Castle J.C.

Genome Med. 7:118.1-118.7(2015).

Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies.

Golub T.R., Root D.E., Hahn W.C.

Sci. Data 1:140035-140035(2014).

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.

Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.

Nature 483:603-607(2012).

Biology of SNU cell lines.";

Ku J.-L., Park J.-G.

Cancer Res. Treat. 37:1-19(2005).

Establishment and characterization of nine human brain tumor cell lines.

Shin K.-H., Choe G., Park Y.-J., Jang J.-H., Jung H.-W., Park J.-G.

In Vitro Cell. Dev. Biol. Anim. 37:625-628(2001).