SNU-251Homo sapiens (Human)Cancer cell line
Also known as: SNU251
AI Summary
No AI-generated summary available for this cell line.
Basic Information
| Database ID | CVCL_5040 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Ascites[UBERON:UBERON_0007795] |
Donor Information
| Age | 47 |
|---|---|
| Age Category | Adult |
| Sex | Female |
Disease Information
| Disease | Endometrioid carcinoma of ovary |
|---|---|
| Lineage | Ovary/Fallopian Tube |
| Subtype | Endometrioid Ovarian Cancer |
| OncoTree Code | EOV |
DepMap Information
| Source Type | KCLB |
|---|---|
| Source ID | ACH-002524_source |
Known Sequence Variations
| Type | Gene/Protein | Description | Zygosity | Note | Source |
|---|---|---|---|---|---|
| MutationSimple | MLH1 | p.Ala723Asp (c.2168C>A) | Heterozygous | - | PubMed=9299249 |
| MutationSimple | BRCA1 | p.Trp1815Ter (c.5445G>A) | Hemizygous or homozygous | - | PubMed=9299249 |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Amelogenin
X
CSF1PO
10,12
D13S317
9
D16S539
11
D18S51
14,15
D19S433
13.2,14.2
D21S11
30,31.2
D2S1338
19,22
D3S1358
15,16
D5S818
11
D7S820
10,12
D8S1179
11,13
FGA
20
TH01
8
TPOX
12
vWA
15,18
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines
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Publications
BRCA1/2 mutation analysis in 41 ovarian cell lines reveals only one functionally deleterious BRCA1 mutation.
Mills G.B., Hennessy B.T.
Mol. Oncol. 7:567-579(2013).
DNA profiling analysis of endometrial and ovarian cell lines reveals misidentification, redundancy and contamination.
Lessey B.A., Jordan V.C., Bradford A.P.
Gynecol. Oncol. 127:241-248(2012).