SNU-254Homo sapiens (Human)Cancer cell line
Also known as: SNU254
AI Summary
No AI-generated summary available for this cell line.
Basic Information
| Database ID | CVCL_5041 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Rectum[UBERON:UBERON_0001052] |
Donor Information
| Age | 61 |
|---|---|
| Age Category | Adult |
| Sex | Female |
Disease Information
| Disease | Rectal adenocarcinoma |
|---|---|
| Lineage | Bowel |
| Subtype | Rectal Adenocarcinoma |
| OncoTree Code | READ |
DepMap Information
| Source Type | KCLB |
|---|---|
| Source ID | ACH-002535_source |
Known Sequence Variations
| Type | Gene/Protein | Description | Zygosity | Note | Source |
|---|---|---|---|---|---|
| MutationSimple | TP53 | p.Glu286Lys (c.856G>A) | Homozygous | - | PubMed=17332242, PubMed=16960149 |
| MutationSimple | KRAS | p.Gly12Asp (c.35G>A) | Unspecified | - | PubMed=29786757 |
| MutationSimple | APC | p.Leu1488Tyrfs*19 (c.4463delT) | Unspecified | - | PubMed=20176655 |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Amelogenin
X
CSF1PO
10,11
D13S317
11
D16S539
9
D18S51
12
D19S433
12,15.2
D21S11
31
D2S1338
23
D3S1358
16,17
D5S818
10,11
D7S820
11,13
D8S1179
13,15
FGA
24,25
TH01
7
TPOX
8,12
vWA
14,17
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines
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Publications
The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets.
Linnebacher M., Cordero F., Di Nicolantonio F., Bardelli A.
Nat. Commun. 6:7002.1-7002.10(2015).