SNU-324Homo sapiens (Human)Cancer cell line

Also known as: NCI-SNU-324, SNU324

AI Summary

No AI-generated summary available for this cell line.

Basic Information

Database IDCVCL_5051
SpeciesHomo sapiens (Human)
Tissue SourcePancreas[UBERON:UBERON_0001264]

Donor Information

Age50
Age CategoryAdult
SexMale
Raceasian

Disease Information

DiseasePancreatic adenocarcinoma
LineagePancreas
SubtypePancreatic Adenocarcinoma
OncoTree CodePAAD

DepMap Information

Source TypeKCLB
Source IDACH-000933_source

Known Sequence Variations

TypeGene/ProteinDescriptionZygosityNoteSource
Gene fusionALKEML4-ALK-E6A20 v3 fusionPubMed=35933914, PubMed=31882684

Haplotype Information (STR Profile)

Short Tandem Repeat (STR) profile for cell line authentication.

CSF1PO
10,11
D13S317
9,11
D3S1358
15,16
D5S818
10,11
D7S820
11
FGA
21,22
TH01
7,9
TPOX
10,11
vWA
18,19
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines

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Publications

Next-generation characterization of the Cancer Cell Line Encyclopedia.

Sellers W.R.

Nature 569:503-508(2019).

An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.

Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.

Cancer Res. 79:1263-1273(2019).

TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.

Loewer M., Sahin U., Castle J.C.

Genome Med. 7:118.1-118.7(2015).

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.

Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.

Nature 483:603-607(2012).

Biology of SNU cell lines.";

Ku J.-L., Park J.-G.

Cancer Res. Treat. 37:1-19(2005).

Establishment and characterization of four human pancreatic carcinoma cell lines. Genetic alterations in the TGFBR2 gene but not in the MADH4 gene.

Park Y.-H., Park J.-G.

Cell Tissue Res. 308:205-214(2002).

Distribution of characteristic mutations in native ductal adenocarcinoma of the pancreas and pancreatic cancer cell lines.

Saeger H.-D.

Cell Biol. Res. Ther. 2:1000104.1-1000104.5(2013).