SNU-46Homo sapiens (Human)Cancer cell line
Also known as: SNU46
AI Summary
No AI-generated summary available for this cell line.
Basic Information
| Database ID | CVCL_5063 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Larynx[UBERON:UBERON_0001737] |
Donor Information
| Age | 65 |
|---|---|
| Age Category | Adult |
| Sex | Male |
| Race | asian |
Disease Information
| Disease | Squamous cell carcinoma of the larynx |
|---|---|
| Lineage | Head and Neck |
| Subtype | Larynx Squamous Cell Carcinoma |
| OncoTree Code | LXSC |
DepMap Information
| Source Type | KCLB |
|---|---|
| Source ID | ACH-000500_source |
Known Sequence Variations
| Type | Gene/Protein | Description | Zygosity | Note | Source |
|---|---|---|---|---|---|
| MutationSimple | TP53 | p.Gly245Cys (c.733G>T) | Heterozygous | Somatic mutation acquired during proliferation | PubMed=18487078, PubMed=16020667, PubMed=15287027, PubMed=12884349, PubMed=1394225 |
| MutationSimple | CDKN2A | p.Pro114His (c.341C>A) (p.Ala128Ala, c.384C>A) | Homozygous | - | Unknown, PubMed=10369293 |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Amelogenin
X
CSF1PO
10,12
D13S317
11
D3S1358
15
D5S818
11
D7S820
10,11
FGA
21,24
TH01
9
TPOX
8,11
vWA
15,16
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines
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Publications
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Sellers W.R.
Nature 569:503-508(2019).
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
Cancer Res. 79:1263-1273(2019).
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
Nature 483:603-607(2012).