SNU-478Homo sapiens (Human)Cancer cell line
Also known as: NCI-SNU-478, SNU478
No AI-generated summary available for this cell line.
Basic Information
| Database ID | CVCL_5065 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Pancreas, ampulla of Vater[UBERON:UBERON_0004913] |
Donor Information
| Age Category | Unknown |
|---|---|
| Sex | Unknown |
| Race | asian |
Disease Information
| Disease | Carcinoma of the ampulla of Vater |
|---|---|
| Lineage | Ampulla of Vater |
| Subtype | Ampullary Carcinoma |
| OncoTree Code | AMPCA |
DepMap Information
| Source Type | KCLB |
|---|---|
| Source ID | ACH-000377_source |
Known Sequence Variations
| Type | Gene/Protein | Description | Zygosity | Note | Source |
|---|---|---|---|---|---|
| MutationSimple | TP53 | p.Gly266fs*4 (c.797_801delGACGG) | Homozygous | - | Unknown, PubMed=12107841 |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Loading gene expression data...
Publications
Generation of a biliary tract cancer cell line atlas reveals molecular subtypes and therapeutic targets.
Vazquez F., Getz G., Bardeesy N.M.
bioRxiv 2024:07.04.601970-07.04.601970(2024).
RNA sequencing of hepatobiliary cancer cell lines: data and applications to mutational and transcriptomic profiling.
Umu S.U., Rounge T.B., Roessler S., Lorenzo-Bermejo J.
Cancers (Basel) 12:2510.1-2510.14(2020).
Comprehensive transcriptomic analysis of cell lines as models of primary tumors across 22 tumor types.
van 't Veer L.J., Butte A.J., Goldstein T., Sirota M.
Nat. Commun. 10:3574.1-3574.11(2019).
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Sellers W.R.
Nature 569:503-508(2019).
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
Cancer Res. 79:1263-1273(2019).
Isocitrate dehydrogenase mutations confer dasatinib hypersensitivity and SRC dependence in intrahepatic cholangiocarcinoma.
Bardeesy N.M.
Cancer Discov. 6:727-739(2016).
Characterization of various cell lines from different ampullary cancer subtypes and cancer associated fibroblast-mediated responses.
Schilling O., Bronsert P., Wellner U.F.
BMC Cancer 16:195.1-195.17(2016).
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
Loewer M., Sahin U., Castle J.C.
Genome Med. 7:118.1-118.7(2015).
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
Nature 483:603-607(2012).