SNU-503Homo sapiens (Human)Cancer cell line
Also known as: NCI-SNU-503, SNU503
AI Summary
No AI-generated summary available for this cell line.
Basic Information
| Database ID | CVCL_5071 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Abdominal wall[UBERON:UBERON_0003697] |
Donor Information
| Age | 52 |
|---|---|
| Age Category | Adult |
| Sex | Male |
| Race | asian |
Disease Information
| Disease | Rectal adenocarcinoma |
|---|---|
| Lineage | Bowel |
| Subtype | Rectal Adenocarcinoma |
| OncoTree Code | READ |
DepMap Information
| Source Type | KCLB |
|---|---|
| Source ID | ACH-000683_source |
Known Sequence Variations
| Type | Gene/Protein | Description | Zygosity | Note | Source |
|---|---|---|---|---|---|
| MutationSimple | TP53 | p.Arg273Leu (c.818G>T) | Homozygous | Somatic mutation acquired during proliferation | PubMed=31541927, PubMed=23613873, PubMed=15735012 |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Amelogenin
X
CSF1PO
11
D13S317
10
D16S539
11,12
D21S11
30
D3S1358
15
D5S818
10
D7S820
10
FGA
22
TH01
9
TPOX
8,11
vWA
14,17
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines
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Publications
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Sellers W.R.
Nature 569:503-508(2019).
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
Cancer Res. 79:1263-1273(2019).
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
Loewer M., Sahin U., Castle J.C.
Genome Med. 7:118.1-118.7(2015).
The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets.
Linnebacher M., Cordero F., Di Nicolantonio F., Bardelli A.
Nat. Commun. 6:7002.1-7002.10(2015).
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
Nature 483:603-607(2012).
Mutations in hMSH6 alone are not sufficient to cause the microsatellite instability in colorectal cancer cell lines.
Ku J.-L., Yoon K.-A., Kim D.-Y., Park J.-G.
Eur. J. Cancer 35:1724-1729(1999).