SNU-520Homo sapiens (Human)Cancer cell line

Also known as: NCI-SNU-520, SNU520

AI Summary

No AI-generated summary available for this cell line.

Basic Information

Database IDCVCL_5072
SpeciesHomo sapiens (Human)
Tissue SourceStomach[UBERON:UBERON_0000945]

Donor Information

Age60
Age CategoryAdult
SexFemale
Raceasian

Disease Information

DiseaseGastric adenocarcinoma
LineageEsophagus/Stomach
SubtypeStomach Adenocarcinoma
OncoTree CodeSTAD

DepMap Information

Source TypeKCLB
Source IDACH-000908_source

Known Sequence Variations

TypeGene/ProteinDescriptionZygosityNoteSource
MutationNone reportedTP53---PubMed=19787792
MutationSimplePTENp.Lys267Argfs*9 (c.800delA) (p.Leu265fs, c.795delA)Heterozygous-Unknown, Unknown, PubMed=25230021

Haplotype Information (STR Profile)

Short Tandem Repeat (STR) profile for cell line authentication.

Amelogenin
X
CSF1PO
10,11
D13S317
8
D3S1358
14,15
D5S818
10,13
D7S820
9,11
FGA
21
TH01
8,9
TPOX
7,8
vWA
17,18
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines

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Publications

Next-generation characterization of the Cancer Cell Line Encyclopedia.

Sellers W.R.

Nature 569:503-508(2019).

An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.

Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.

Cancer Res. 79:1263-1273(2019).

TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.

Loewer M., Sahin U., Castle J.C.

Genome Med. 7:118.1-118.7(2015).

A catalog of HLA type, HLA expression, and neo-epitope candidates in human cancer cell lines.

Boegel S., Lower M., Bukur T., Sahin U., Castle J.C.

OncoImmunology 3:e954893.1-e954893.12(2014).

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.

Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.

Nature 483:603-607(2012).

Biology of SNU cell lines.";

Ku J.-L., Park J.-G.

Cancer Res. Treat. 37:1-19(2005).

Establishment and characterization of human gastric carcinoma cell lines.

Bang Y.-J., Kim Y.I., Kim J.-P.

Int. J. Cancer 70:443-449(1997).