SNU-685Homo sapiens (Human)Cancer cell line

Also known as: NCI-SNU-685, SNU685

AI Summary

No AI-generated summary available for this cell line.

Basic Information

Database IDCVCL_5083
SpeciesHomo sapiens (Human)
Tissue SourceEndometrium[UBERON:UBERON_0001295]

Donor Information

Age70
Age CategoryAdult
SexFemale
Raceasian

Disease Information

DiseaseCarcinosarcoma of the corpus uteri
LineageUterus
SubtypeUterine Carcinosarcoma/Uterine Malignant Mixed Mullerian Tumor
OncoTree CodeUCS

DepMap Information

Source TypeKCLB
Source IDACH-000407_source

Known Sequence Variations

TypeGene/ProteinDescriptionZygosityNoteSource
MutationSimpleTP53c.919+1G>T (IVS8+1G>T)HomozygousSplice donor mutationUnknown

Haplotype Information (STR Profile)

Short Tandem Repeat (STR) profile for cell line authentication.

Amelogenin
X
CSF1PO
11
D13S317
8
D3S1358
14
D5S818
12
D7S820
8,12
FGA
21
TH01
6,9.3
TPOX
9
vWA
17,19
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines

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Publications

Quantitative proteomics of the Cancer Cell Line Encyclopedia.";

Sellers W.R., Gygi S.P.

Cell 180:387-402.e16(2020).

Next-generation characterization of the Cancer Cell Line Encyclopedia.

Sellers W.R.

Nature 569:503-508(2019).

An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.

Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.

Cancer Res. 79:1263-1273(2019).

TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.

Loewer M., Sahin U., Castle J.C.

Genome Med. 7:118.1-118.7(2015).

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.

Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.

Nature 483:603-607(2012).

Biology of SNU cell lines.";

Ku J.-L., Park J.-G.

Cancer Res. Treat. 37:1-19(2005).

Establishment and characterization of cell lines derived from uterine malignant mixed Mullerian tumor.

Kang S.-B., Park J.-G.

Gynecol. Oncol. 66:464-474(1997).