SNU-719Homo sapiens (Human)Cancer cell line

Also known as: NCI-SNU-719, SNU719

AI Summary

No AI-generated summary available for this cell line.

Basic Information

Database IDCVCL_5086
SpeciesHomo sapiens (Human)
Tissue SourceStomach[UBERON:UBERON_0000945]

Donor Information

Age53
Age CategoryAdult
SexMale
Raceasian

Disease Information

DiseaseGastric tubular adenocarcinoma
LineageEsophagus/Stomach
SubtypeTubular Stomach Adenocarcinoma
OncoTree CodeTSTAD

DepMap Information

Source TypeKCLB
Source IDACH-000898_source

Known Sequence Variations

TypeGene/ProteinDescriptionZygosityNoteSource
MutationNone reportedTP53---PubMed=19787792
MutationSimplePIK3CAp.Pro104Arg (c.311C>G)Heterozygous-from parent cell line SNU-719
MutationSimpleNRASp.Gln61Leu (c.182A>T)Unspecified-PubMed=26214590
MutationSimpleMETp.Asp153Ala (c.458A>C)Heterozygous-from parent cell line SNU-719
MutationSimpleCTNNB1p.Gly34Val (c.101G>T)Unspecified-Unknown

Haplotype Information (STR Profile)

Short Tandem Repeat (STR) profile for cell line authentication.

Amelogenin
X,Y
CSF1PO
12
D13S317
10,11
D16S539
9,10
D18S51
13,15
D21S11
29,30
D3S1358
15
D5S818
11,12
D7S820
10,11
D8S1179
12
FGA
21,23
Penta D
10,11
Penta E
11,16
TH01
7,9
TPOX
8,9
vWA
16,18
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines

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Publications

Quantitative proteomics of the Cancer Cell Line Encyclopedia.";

Sellers W.R., Gygi S.P.

Cell 180:387-402.e16(2020).

Next-generation characterization of the Cancer Cell Line Encyclopedia.

Sellers W.R.

Nature 569:503-508(2019).

An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.

Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.

Cancer Res. 79:1263-1273(2019).

Forty-nine gastric cancer cell lines with integrative genomic profiling for development of c-MET inhibitor.

Kragh M., Horak I.D., Chung H.C., Rha S.Y.

Int. J. Cancer 143:151-159(2018).

Highly efficient CRISPR/Cas9-mediated cloning and functional characterization of gastric cancer-derived Epstein-Barr virus strains.

Kanda T., Furuse Y., Oshitani H., Kiyono T.

J. Virol. 90:4383-4393(2016).

TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.

Loewer M., Sahin U., Castle J.C.

Genome Med. 7:118.1-118.7(2015).

A catalog of HLA type, HLA expression, and neo-epitope candidates in human cancer cell lines.

Boegel S., Lower M., Bukur T., Sahin U., Castle J.C.

OncoImmunology 3:e954893.1-e954893.12(2014).

A resource for cell line authentication, annotation and quality control.

Neve R.M.

Nature 520:307-311(2015).

A comprehensive transcriptional portrait of human cancer cell lines.

Settleman J., Seshagiri S., Zhang Z.-M.

Nat. Biotechnol. 33:306-312(2015).

Integrated exome and transcriptome sequencing reveals ZAK isoform usage in gastric cancer.

Firestein R., Zhang Z.-M.

Nat. Commun. 5:3830.1-3830.8(2014).

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.

Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.

Nature 483:603-607(2012).

Biology of SNU cell lines.";

Ku J.-L., Park J.-G.

Cancer Res. Treat. 37:1-19(2005).

Screening of DNA copy-number aberrations in gastric cancer cell lines by array-based comparative genomic hybridization.

Okanoue T., Inazawa J.

Cancer Sci. 96:100-110(2005).

A naturally derived gastric cancer cell line shows latency I Epstein-Barr virus infection closely resembling EBV-associated gastric cancer.

Kim W.-H., Park J.-G., Lee S.K.

Virology 320:330-336(2004).

Characterization of chromosomal aberrations in human gastric carcinoma cell lines using chromosome painting.

Chun Y.-H., Kil J.-I., Suh Y.-S., Kim S.-H., Kim H., Park S.-H.

Cancer Genet. Cytogenet. 119:18-25(2000).

Establishment and characterization of human gastric carcinoma cell lines.

Bang Y.-J., Kim Y.I., Kim J.-P.

Int. J. Cancer 70:443-449(1997).