SNU-869Homo sapiens (Human)Cancer cell line
Also known as: SNU869
AI Summary
No AI-generated summary available for this cell line.
Basic Information
| Database ID | CVCL_5101 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Pancreas, ampulla of Vater[UBERON:UBERON_0004913] |
Donor Information
| Age Category | Unknown |
|---|---|
| Sex | Unknown |
| Race | asian |
Disease Information
| Disease | Carcinoma of the ampulla of Vater |
|---|---|
| Lineage | Ampulla of Vater |
| Subtype | Ampullary Carcinoma |
| OncoTree Code | AMPCA |
DepMap Information
| Source Type | KCLB |
|---|---|
| Source ID | ACH-000182_source |
Known Sequence Variations
| Type | Gene/Protein | Description | Zygosity | Note | Source |
|---|---|---|---|---|---|
| MutationSimple | TP53 | p.Asp48Gly (c.143A>G) | Unspecified | - | PubMed=12107841 |
| MutationSimple | PIK3CA | p.Glu545Asp (c.1635G>T) | Heterozygous | - | from parent cell line SupT1/Blam |
| MutationSimple | KRAS | p.Gly12Asp (c.35G>A) | Unspecified | - | PubMed=29786757 |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
CSF1PO
10
D13S317
12
D3S1358
15
D5S818
12
D7S820
8,11
FGA
23
TH01
7,9
TPOX
8,10
vWA
15
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines
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Publications
Generation of a biliary tract cancer cell line atlas reveals molecular subtypes and therapeutic targets.
Vazquez F., Getz G., Bardeesy N.M.
bioRxiv 2024:07.04.601970-07.04.601970(2024).
Comprehensive transcriptomic analysis of cell lines as models of primary tumors across 22 tumor types.
van 't Veer L.J., Butte A.J., Goldstein T., Sirota M.
Nat. Commun. 10:3574.1-3574.11(2019).
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Sellers W.R.
Nature 569:503-508(2019).
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
Cancer Res. 79:1263-1273(2019).
Isocitrate dehydrogenase mutations confer dasatinib hypersensitivity and SRC dependence in intrahepatic cholangiocarcinoma.
Bardeesy N.M.
Cancer Discov. 6:727-739(2016).
Characterization of various cell lines from different ampullary cancer subtypes and cancer associated fibroblast-mediated responses.
Schilling O., Bronsert P., Wellner U.F.
BMC Cancer 16:195.1-195.17(2016).
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
Loewer M., Sahin U., Castle J.C.
Genome Med. 7:118.1-118.7(2015).