SH-10-TCHomo sapiens (Human)Cancer cell line
Also known as: SH-10, SH10TC
AI Summary
No AI-generated summary available for this cell line.
Basic Information
| Database ID | CVCL_5167 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Stomach[UBERON:UBERON_0000945] |
Donor Information
| Age Category | Unknown |
|---|---|
| Sex | Unknown |
Disease Information
| Disease | Gastric mucinous adenocarcinoma |
|---|---|
| Lineage | Esophagus/Stomach |
| Subtype | Mucinous Stomach Adenocarcinoma |
| OncoTree Code | MSTAD |
DepMap Information
| Source Type | RIKEN |
|---|---|
| Source ID | ACH-000764_source |
Known Sequence Variations
| Type | Gene/Protein | Description | Zygosity | Note | Source |
|---|---|---|---|---|---|
| MutationSimple | TP53 | p.Arg273Cys (c.817C>T) | Homozygous | - | PubMed=35933914 |
| MutationSimple | TERT | c.1-124C>T (c.228C>T) (C228T) | Unspecified | In promoter | from parent cell line Hep-G2 |
| MutationSimple | KRAS | p.Gly12Val (c.35G>T) | Heterozygous | Acquired | Unknown, Unknown |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Amelogenin
X
CSF1PO
13
D13S317
11
D16S539
11,13
D5S818
12
D7S820
11
TH01
7,9
TPOX
8,11
vWA
17,18
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines
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Publications
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Sellers W.R.
Nature 569:503-508(2019).
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
Cancer Res. 79:1263-1273(2019).