LC-1/sq-SFHomo sapiens (Human)Cancer cell line

Also known as: LC-1/sq-Serum Free, LC1SQSF, LC-1-sq-SF, LC1_sq-SF

AI Summary

No AI-generated summary available for this cell line.

Basic Information

Database IDCVCL_5480
SpeciesHomo sapiens (Human)
Tissue SourceLung[UBERON:UBERON_0002048]

Donor Information

Age69
Age CategoryAdult
SexMale
Raceasian

Disease Information

DiseaseLung squamous cell carcinoma
LineageLung
SubtypeLung Squamous Cell Carcinoma
OncoTree CodeLUSC

DepMap Information

Source TypeRIKEN
Source IDACH-001113_source

Known Sequence Variations

TypeGene/ProteinDescriptionZygosityNoteSource
MutationSimpleTP53p.Met237Ile (c.711G>T)Unspecified-from parent cell line T98G
MutationSimpleSPENp.Arg1475Ter (c.4423C>T)Heterozygous-Unknown

Haplotype Information (STR Profile)

Short Tandem Repeat (STR) profile for cell line authentication.

Amelogenin
X
CSF1PO
12
D13S317
12,13
D16S539
9
D5S818
12,13
D7S820
12
TH01
7,9
TPOX
8,12
vWA
17,18
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines

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Publications

Next-generation characterization of the Cancer Cell Line Encyclopedia.

Sellers W.R.

Nature 569:503-508(2019).

An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.

Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.

Cancer Res. 79:1263-1273(2019).

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.

Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.

Nature 483:603-607(2012).