CH-157MNHomo sapiens (Human)Cancer cell line

Also known as: CH157MN, CH-157 MN, CH-157-MN, CH157-MN

AI Summary

No AI-generated summary available for this cell line.

Basic Information

Database IDCVCL_5723
SpeciesHomo sapiens (Human)
Tissue SourceBrain, meninges[UBERON:UBERON_0010743]

Donor Information

Age41
Age CategoryAdult
SexFemale

Disease Information

DiseaseMeningioma
LineageCNS/Brain
SubtypeMeningioma
OncoTree CodeMNG

DepMap Information

Source TypeAcademic lab
Source IDACH-000025_source

Known Sequence Variations

TypeGene/ProteinDescriptionZygosityNoteSource
MutationSimpleTERTc.1-124C>T (c.228C>T) (C228T)UnspecifiedIn promoterfrom parent cell line Hep-G2
MutationSimpleNRASp.Gln61Lys (c.181C>A)UnspecifiedAcquired during resistance selection processPubMed=26214590
Gene Expression Profile
Gene expression levels and statistical distribution
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Publications

Tumor-derived cell culture model for the investigation of meningioma biology.

Anderson M.P., Uhlmann E.N., Kipper F.C., Krichevsky A.M.

J. Neuropathol. Exp. Neurol. 80:1117-1124(2021).

Next-generation characterization of the Cancer Cell Line Encyclopedia.

Sellers W.R.

Nature 569:503-508(2019).

An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.

Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.

Cancer Res. 79:1263-1273(2019).

Genomic profile of human meningioma cell lines.";

Dunn I.F.

PLoS ONE 12:E0178322-E0178322(2017).

Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies.

Golub T.R., Root D.E., Hahn W.C.

Sci. Data 1:140035-140035(2014).

A comparison of the cell lines used in meningioma research.";

Jensen R.L.

Surg. Neurol. 70:295-307(2008).

Regulation of vascular endothelial growth factor secretion in human meningioma cells.

Goldman C.K., Kao M.-C.

J. Formos. Med. Assoc. 98:111-117(1999).

Vascular endothelial growth factor in human glioma cell lines: induced secretion by EGF, PDGF-BB, and bFGF.

Tsai J.-C., Goldman C.K., Gillespie G.Y.

J. Neurosurg. 82:864-873(1995).