TUHR4TKBHomo sapiens (Human)Cancer cell line

Also known as: 4T, 4TUHR, TUHR-4TKB

AI Summary

No AI-generated summary available for this cell line.

Basic Information

Database IDCVCL_5957
SpeciesHomo sapiens (Human)
Tissue SourceKidney[UBERON:UBERON_0002113]

Donor Information

Age60
Age CategoryAdult
SexMale

Disease Information

DiseaseRenal cell carcinoma
LineageKidney
SubtypeRenal Cell Carcinoma
OncoTree CodeRCC

DepMap Information

Source TypeRIKEN
Source IDACH-000495_source

Haplotype Information (STR Profile)

Short Tandem Repeat (STR) profile for cell line authentication.

Amelogenin
X
CSF1PO
12
D13S317
8,11
D16S539
11,12
D5S818
10,12
D7S820
12,13
TH01
9
TPOX
11
vWA
15,17
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines

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Publications

Quantitative proteomics of the Cancer Cell Line Encyclopedia.";

Sellers W.R., Gygi S.P.

Cell 180:387-402.e16(2020).

Next-generation characterization of the Cancer Cell Line Encyclopedia.

Sellers W.R.

Nature 569:503-508(2019).

An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.

Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.

Cancer Res. 79:1263-1273(2019).

Analysis of renal cancer cell lines from two major resources enables genomics-guided cell line selection.

Hsieh J.J.-D., Hakimi A.A.

Nat. Commun. 8:15165.1-15165.10(2017).

TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.

Loewer M., Sahin U., Castle J.C.

Genome Med. 7:118.1-118.7(2015).

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.

Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.

Nature 483:603-607(2012).

Downregulation of SAV1 plays a role in pathogenesis of high-grade clear cell renal cell carcinoma.

Mimata H., Seto M., Moriyama M.

BMC Cancer 11:523.1-523.10(2011).

Comparative antitumor activity of 5-fluorouracil and 5'-deoxy-5-fluorouridine in combination with interferon-alpha in renal cell carcinoma cell lines.

Nakatani T.

Urol. Int. 73:348-353(2004).

Effects of tumor necrosis factor alpha in renal cell carcinoma.";

Nakatani T.

Oncol. Rep. 10:1947-1955(2003).

Expression of the SART1 tumor rejection antigen in renal cell carcinoma.

Yoshizumi O., Itoh K.

Urol. Res. 28:178-184(2000).

High rate of induction of human autologous cytotoxic T lymphocytes against renal carcinoma cells cultured with an interleukin cocktail.

Shiba R., Saijo K., Ohno T.

Jpn. J. Cancer Res. 89:1195-1201(1998).