CHLA-10Homo sapiens (Human)Cancer cell line
Also known as: CHLA10
AI Summary
No AI-generated summary available for this cell line.
Basic Information
Database ID | CVCL_6583 |
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Species | Homo sapiens (Human) |
Tissue Source | Thoracic lymph duct[UBERON:UBERON_0007644] |
Donor Information
Age | 14 |
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Age Category | Pediatric |
Sex | Female |
Subtype Features | EWS-FLI |
Disease Information
Disease | Primitive neuroectodermal tumor |
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Lineage | Bone |
Subtype | Ewing Sarcoma |
OncoTree Code | ES |
DepMap Information
Source Type | Academic lab |
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Source ID | ACH-001029_source |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Amelogenin
X
CSF1PO
12
D13S317
12
D16S539
11
D18S51
12,14
D19S433
12,13
D21S11
28,29
D2S1338
20
D3S1358
15
D5S818
12
D7S820
9,10
D8S1179
10,13
FGA
23
TH01
7
TPOX
11
vWA
16
Gene Expression Profile
Gene expression levels and statistical distribution
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Publications
Characterization of human cancer cell lines by reverse-phase protein arrays.
Liang H.
Cancer Cell 31:225-239(2017).
Sarcoma cell line screen of oncology drugs and investigational agents identifies patterns associated with gene and microRNA expression.
Harris E., Monks A., Morris J.
Mol. Cancer Ther. 14:2452-2462(2015).
Characterization and drug resistance patterns of Ewing's sarcoma family tumor cell lines.
Jenabi J., Ji L.-Y., Triche T.J., Lawlor E.R., Reynolds C.P.
PLoS ONE 8:E80060-E80060(2013).
National Cancer Institute pediatric preclinical testing program: model description for in vitro cytotoxicity testing.
Reynolds C.P.
Pediatr. Blood Cancer 56:239-249(2011).
Fenretinide cytotoxicity for Ewing's sarcoma and primitive neuroectodermal tumor cell lines is decreased by hypoxia and synergistically enhanced by ceramide modulators.
Batra S., Reynolds C.P., Maurer B.J.
Cancer Res. 64:5415-5424(2004).
Homozygous deletion of CDKN2A (p16INK4a/p14ARF) but not within 1p36 or at other tumor suppressor loci in neuroblastoma.
Brodeur G.M., White P.S.
Cancer Res. 61:679-686(2001).
Systematic multi-omics profiling of Ewing sarcoma cell lines.";
Orth M.F.
Thesis PhD (2021); Ludwig Maximilians University of Munich; Munich; Germany.