TM-31Homo sapiens (Human)Cancer cell line

Also known as: TM31

AI Summary

No AI-generated summary available for this cell line.

Basic Information

Database IDCVCL_6735
SpeciesHomo sapiens (Human)
Tissue SourceBrain[UBERON:UBERON_0000955]

Donor Information

Age42
Age CategoryAdult
SexFemale

Disease Information

DiseaseNeurofibromatosis type 1
LineageCNS/Brain
SubtypeAstrocytoma
OncoTree CodeASTR

DepMap Information

Source TypeRIKEN
Source IDACH-000592_source

Known Sequence Variations

TypeGene/ProteinDescriptionZygosityNoteSource
MutationSimpleTP53p.Cys238Gly (c.712T>G)Homozygous-Unknown, PubMed=11213969

Haplotype Information (STR Profile)

Short Tandem Repeat (STR) profile for cell line authentication.

Amelogenin
X
CSF1PO
11,12
D13S317
11,14
D16S539
9,12
D5S818
10
D7S820
11,12
TH01
9
TPOX
8,11
vWA
19
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines

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Publications

Comprehensive transcriptomic analysis of cell lines as models of primary tumors across 22 tumor types.

van 't Veer L.J., Butte A.J., Goldstein T., Sirota M.

Nat. Commun. 10:3574.1-3574.11(2019).

Next-generation characterization of the Cancer Cell Line Encyclopedia.

Sellers W.R.

Nature 569:503-508(2019).

An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.

Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.

Cancer Res. 79:1263-1273(2019).

TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.

Loewer M., Sahin U., Castle J.C.

Genome Med. 7:118.1-118.7(2015).

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.

Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.

Nature 483:603-607(2012).

Astrocytoma cell line.";

Couldwell W.T.

J. Neurosurg. 94:348-349(2001).

Establishment and characterization of a novel malignant astrocytoma cell line derived from a tumor removed in a patient with neurofibromatosis type 1.

Endo S.

J. Neurosurg. 94:301-308(2001).