OMM-1Homo sapiens (Human)Cancer cell line
Also known as: Omm1, OMM1
AI Summary
No AI-generated summary available for this cell line.
Basic Information
| Database ID | CVCL_6939 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Hypodermis[UBERON:UBERON_0002072] |
Donor Information
| Age | 74 |
|---|---|
| Age Category | Adult |
| Sex | Male |
Disease Information
| Disease | Uveal melanoma |
|---|---|
| Lineage | Eye |
| Subtype | Uveal Melanoma |
| OncoTree Code | UM |
DepMap Information
| Source Type | Academic lab |
|---|---|
| Source ID | ACH-002017_source |
Known Sequence Variations
| Type | Gene/Protein | Description | Zygosity | Note | Source |
|---|---|---|---|---|---|
| MutationSimple | GNA11 | p.Gln209Leu (c.626A>T) | Unspecified | - | PubMed=22236444 |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Amelogenin
X
CSF1PO
10,12
D13S317
11,12
D16S539
9
D18S51
13,14
D21S11
30,30.2
D3S1358
14,17
D5S818
11
D7S820
13
D8S1179
10,16
FGA
20
Penta D
9,12
Penta E
5,7
TH01
7
TPOX
8,9
vWA
19
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines
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Publications
Establishment of novel cell lines recapitulating the genetic landscape of uveal melanoma and preclinical validation of mTOR as a therapeutic target.
Roman-Roman S.
Mol. Oncol. 8:1508-1520(2014).
Evidence of epidermal growth factor receptor expression in uveal melanoma: inhibition of epidermal growth factor-mediated signalling by gefitinib and cetuximab triggered antibody-dependent cellular cytotoxicity.
Salvi S., Truini M., Poggi A., Pfeffer U.
Eur. J. Cancer 49:3353-3365(2013).
Genetic and molecular characterization of uveal melanoma cell lines.
Bernatchez C., Wardell S., Bastian B.C., Woodman S.E.
Pigment Cell Melanoma Res. 25:182-187(2012).
Molecular cytogenetic evaluation of 10 uveal melanoma cell lines.";
White J.S., Becker R.L., McLean I.W., Director-Myska A.E., Nath J.
Cancer Genet. Cytogenet. 168:11-21(2006).