253JHomo sapiens (Human)Cancer cell line
Also known as: 253JP, 253J P, 253J-Parental, 253J-P, 253 J, 253-J, 253j
No AI-generated summary available for this cell line.
Basic Information
| Database ID | CVCL_7935 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Retroperitoneal lymph node[UBERON:UBERON_0035371] |
Donor Information
| Age | 53 |
|---|---|
| Age Category | Adult |
| Sex | Male |
Disease Information
| Disease | Bladder carcinoma |
|---|---|
| Lineage | Bladder/Urinary Tract |
| Subtype | Bladder Urothelial Carcinoma |
| OncoTree Code | BLCA |
DepMap Information
| Source Type | KCLB |
|---|---|
| Source ID | ACH-000011_source |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
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Publications
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Sellers W.R.
Nature 569:503-508(2019).
Systematic review: characteristics and preclinical uses of bladder cancer cell lines.
Zuiverloon T.C.M., de Jong F.C., Costello J.C., Theodorescu D.
Bladder Cancer 4:169-183(2018).
Molecular analysis of urothelial cancer cell lines for modeling tumor biology and drug response.
Tsang S.X., Cai Z.-M., Wu S., Dean M., Costello J.C., Theodorescu D.
Oncogene 36:35-46(2017).
Erratum to: The UBC-40 Urothelial Bladder Cancer cell line index: a genomic resource for functional studies.
Chanock S.J., Valencia A., Real F.X.
BMC Genomics 16:1019.1-1019.2(2015).
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
Loewer M., Sahin U., Castle J.C.
Genome Med. 7:118.1-118.7(2015).
The UBC-40 Urothelial Bladder Cancer cell line index: a genomic resource for functional studies.
Chanock S.J., Valencia A., Real F.X.
BMC Genomics 16:403.1-403.16(2015).
Identification of mutations in distinct regions of p85 alpha in urothelial cancer.
Knowles M.A.
PLoS ONE 8:E84411-E84411(2013).
Comprehensive mutation analysis of the TERT promoter in bladder cancer and detection of mutations in voided urine.
Hurst C.D., Platt F.M., Knowles M.A.
Eur. Urol. 65:367-369(2014).
TSC1 involvement in bladder cancer: diverse effects and therapeutic implications.
Kwiatkowski D.J.
J. Pathol. 230:17-27(2013).
PIK3CA mutations are an early genetic alteration associated with FGFR3 mutations in superficial papillary bladder tumors.
Carrato A., Tardon A., Serra C., Real F.X.
Cancer Res. 66:7401-7404(2006).
Assessment by M-FISH of karyotypic complexity and cytogenetic evolution in bladder cancer in vitro.
Knowles M.A.
Genes Chromosomes Cancer 43:315-328(2005).
Novel chromosome findings in bladder cancer cell lines detected with multiplex fluorescence in situ hybridization.
Young B.D., Oliver R.T.D.
Cancer Genet. Cytogenet. 135:139-146(2002).
Molecular genetic analysis of chromosome 9 candidate tumor-suppressor loci in bladder cancer cell lines.
Coulter J., Kennedy W.J., Skilleter A., Habuchi T., Knowles M.A.
Genes Chromosomes Cancer 34:86-96(2002).
Short tandem repeat profiling provides an international reference standard for human cell lines.
Harrison M., Virmani A.K., Ward T.H., Ayres K.L., Debenham P.G.
Proc. Natl. Acad. Sci. U.S.A. 98:8012-8017(2001).
Human bladder cancer invasion model using rat bladder in vitro and its use to test mechanisms and therapeutic inhibitors of invasion.
Harris A.L.
Br. J. Cancer 84:558-564(2001).
The 9p21 region in bladder cancer cell lines: large homozygous deletion inactivate the CDKN2, CDKN2B and MTAP genes.
Stadler W.M., Olopade O.I.
Urol. Res. 24:239-244(1996).
Isolation and characterization of metastatic variants from human transitional cell carcinoma passaged by orthotopic implantation in athymic nude mice.
Xie B., Fan D., Bucana C.D., Fidler I.J., Killion J.J.
J. Urol. 154:1532-1538(1995).
Presence of glycogen and growth-related variations in 58 cultured human tumor cell lines of various tissue origins.
Rousset M., Zweibaum A., Fogh J.
Cancer Res. 41:1165-1170(1981).
Distinction of seventy-one cultured human tumor cell lines by polymorphic enzyme analysis.
Wright W.C., Daniels W.P., Fogh J.
J. Natl. Cancer Inst. 66:239-247(1981).
Cell surface antigens of human ovarian and endometrial carcinoma defined by mouse monoclonal antibodies.
Mattes M.J., Cordon-Cardo C., Lewis J.L. Jr., Old L.J., Lloyd K.O.
Proc. Natl. Acad. Sci. U.S.A. 81:568-572(1984).
Characterization of a cell line from human transitional cell cancer of the urinary tract.
Hakala T.R., Fraley E.E.
J. Natl. Cancer Inst. 53:1341-1349(1974).
Tissue culture model of transitional cell carcinoma: characterization of twenty-two human urothelial cell lines.
Franks L.M.
Cancer Res. 46:3630-3636(1986).
In vitro cultivation of epithelial cells derived from tumors of the human urinary tract.
Elliott A.Y., Bronson D.L., Stein N., Fraley E.E.
Cancer Res. 36:365-369(1976).
Transitional cell cancer: establishment and characterization of cell lines.
Elliott A.Y., Bronson D.L., Fraley E.E.
Natl. Cancer Inst. Monogr. 49:23-24(1978).
Cultivation, characterization, and identification of human tumor cells with emphasis on kidney, testis, and bladder tumors.
Fogh J.
Natl. Cancer Inst. Monogr. 49:5-9(1978).
One hundred and twenty-seven cultured human tumor cell lines producing tumors in nude mice.
Fogh J., Fogh J.M., Orfeo T.
J. Natl. Cancer Inst. 59:221-226(1977).
Properties of cell lines established from transitional cell cancers of the human urinary tract.
Elliott A.Y., Bronson D.L., Cervenka J., Stein N., Fraley E.E.
Cancer Res. 37:1279-1289(1977).
Establishment and characterization of epithelial cell cultures from tumors of the human urinary tract.
Elliott A.Y., Bronson D.L., Cervenka J., Cleveland P.H., Fraley E.E.
(In book chapter) Cell culture and the application; Acton R. (eds.); pp.711-728; Academic Press; New York; USA (1977).