KMCH-1Homo sapiens (Human)Cancer cell line
Also known as: KMCH, KMCH1
AI Summary
No AI-generated summary available for this cell line.
Basic Information
| Database ID | CVCL_7970 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Liver[UBERON:UBERON_0002107] |
Donor Information
| Age | 52 |
|---|---|
| Age Category | Adult |
| Sex | Male |
Disease Information
| Disease | Combined hepatocellular carcinoma and cholangiocarcinoma |
|---|---|
| Lineage | Liver |
| Subtype | Hepatocellular Carcinoma plus Intrahepatic Cholangiocarcinoma |
| OncoTree Code | HCCIHCH |
DepMap Information
| Source Type | Academic lab |
|---|---|
| Source ID | ACH-001853_source |
Known Sequence Variations
| Type | Gene/Protein | Description | Zygosity | Note | Source |
|---|---|---|---|---|---|
| MutationSimple | PTEN | p.Tyr346Cys (c.1037A>G) | Unspecified | - | Unknown |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Amelogenin
X
CSF1PO
12
D13S317
11
D16S539
10
D18S51
13
D21S11
29
D3S1358
15
D5S818
12,13
D7S820
10,12
D8S1179
10,14
FGA
22
Penta D
9
Penta E
11,18
TH01
9.3
TPOX
8,11
vWA
16
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines
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Publications
Generation of a biliary tract cancer cell line atlas reveals molecular subtypes and therapeutic targets.
Vazquez F., Getz G., Bardeesy N.M.
bioRxiv 2024:07.04.601970-07.04.601970(2024).
Development and characterization of human primary cholangiocarcinoma cell lines.
Glaser S., Kennedy L., Francis H., Zhang W.-J., Alpini G.D., Ekser B.
Am. J. Pathol. 192:1200-1217(2022).
RNA sequencing of hepatobiliary cancer cell lines: data and applications to mutational and transcriptomic profiling.
Umu S.U., Rounge T.B., Roessler S., Lorenzo-Bermejo J.
Cancers (Basel) 12:2510.1-2510.14(2020).
Interferon alfa receptor expression and growth inhibition by interferon alfa in human liver cancer cell lines.
Kojiro M.
Hepatology 29:1708-1717(1999).
CD4+ hepatic cancer-specific cytotoxic T lymphocytes in patients with hepatocellular carcinoma.
Itoh K.
Cell. Immunol. 177:176-181(1997).
HLA-A locus-restricted and tumor-specific CTLs in tumor-infiltrating lymphocytes of patients with non-small cell lung cancer.
Seki N., Hoshino T., Kikuchi M., Hayashi A., Itoh K.
Cell. Immunol. 175:101-110(1997).
Expression of CD44 in human hepatocellular carcinoma cell lines.";
Haramaki M., Yano H., Fukuda K., Momosaki S., Ogasawara S., Kojiro M.
Hepatology 21:1276-1284(1995).