TTC-1240Homo sapiens (Human)Cancer cell line
Also known as: TTC 1240, TTC1240, TTC1204
AI Summary
No AI-generated summary available for this cell line.
Basic Information
| Database ID | CVCL_8002 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Brain[UBERON:UBERON_0000955] |
Donor Information
| Age Category | Pediatric |
|---|---|
| Sex | Female |
Disease Information
| Disease | Rhabdoid tumor |
|---|---|
| Lineage | Kidney |
| Subtype | Rhabdoid Cancer |
| OncoTree Code | MRT |
DepMap Information
| Source Type | Academic lab |
|---|---|
| Source ID | ACH-001210_source |
Known Sequence Variations
| Type | Gene/Protein | Description | Zygosity | Note | Source |
|---|---|---|---|---|---|
| MutationSimple | SMARCB1 | p.Glu216Ter (c.646G>T) | Unspecified | - | PubMed=28945250, PubMed=11921280, PubMed=10602515 |
Gene Expression Profile
Gene expression levels and statistical distribution
Loading cohorts...
Full DepMap dataset with combined data across cell lines
Loading gene expression data...
Publications
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Sellers W.R.
Nature 569:503-508(2019).
SMARCB1 is required for widespread BAF complex-mediated activation of enhancers and bivalent promoters.
Irizarry R.A., Zhao K.-J., Ranish J.A., Kadoch C.
Nat. Genet. 49:1613-1623(2017).
Genome-wide approach to identify second gene targets for malignant rhabdoid tumors using high-density oligonucleotide microarrays.
Ogawa S.
Cancer Sci. 105:258-264(2014).
Expression of pericyte, mesangium and muscle markers in malignant rhabdoid tumor cell lines: differentiation-induction using 5-azacytidine.
Sugita K.
Cancer Sci. 94:1059-1065(2003).
Malignant rhabdoid tumor shows incomplete neural characteristics as revealed by expression of SNARE complex.
Yoshida S., Narita T., Taga T., Ohta S., Takeuchi Y.
J. Neurosci. Res. 69:642-652(2002).
Aberrations of the hSNF5/INI1 gene are restricted to malignant rhabdoid tumors or atypical teratoid/rhabdoid tumors in pediatric solid tumors.
Gilles F.H., Sugita K., Abe S., Sako M., Hashizume K., Hayashi Y.
Genes Chromosomes Cancer 34:33-41(2002).