TTC-549Homo sapiens (Human)Cancer cell line

Also known as: TTC549

AI Summary

No AI-generated summary available for this cell line.

Basic Information

Database IDCVCL_8005
SpeciesHomo sapiens (Human)
Tissue SourceLiver[UBERON:UBERON_0002107]

Donor Information

Age6
Age CategoryPediatric
SexFemale

Disease Information

DiseaseRhabdoid tumor
LineageSoft Tissue
SubtypeExtrarenal Rhabdoid Cancer

DepMap Information

Source TypeAcademic lab
Source IDACH-001211_source

Known Sequence Variations

TypeGene/ProteinDescriptionZygosityNoteSource
Gene deletionSMARCB1-Homozygous-PubMed=11921280
Gene Expression Profile
Gene expression levels and statistical distribution
Loading cohorts...
Full DepMap dataset with combined data across cell lines

Loading gene expression data...

Publications

Next-generation characterization of the Cancer Cell Line Encyclopedia.

Sellers W.R.

Nature 569:503-508(2019).

Genome-wide approach to identify second gene targets for malignant rhabdoid tumors using high-density oligonucleotide microarrays.

Ogawa S.

Cancer Sci. 105:258-264(2014).

Prognostic significance of dysadherin expression in epithelioid sarcoma and its diagnostic utility in distinguishing epithelioid sarcoma from malignant rhabdoid tumor.

Saito T., Yamamoto H., Tamiya S., Iwamoto Y., Tsuneyoshi M.

Mod. Pathol. 19:820-831(2006).

Expression of pericyte, mesangium and muscle markers in malignant rhabdoid tumor cell lines: differentiation-induction using 5-azacytidine.

Sugita K.

Cancer Sci. 94:1059-1065(2003).

Malignant rhabdoid tumor shows incomplete neural characteristics as revealed by expression of SNARE complex.

Yoshida S., Narita T., Taga T., Ohta S., Takeuchi Y.

J. Neurosci. Res. 69:642-652(2002).

Aberrations of the hSNF5/INI1 gene are restricted to malignant rhabdoid tumors or atypical teratoid/rhabdoid tumors in pediatric solid tumors.

Gilles F.H., Sugita K., Abe S., Sako M., Hashizume K., Hayashi Y.

Genes Chromosomes Cancer 34:33-41(2002).

Subcellular distribution of cytokeratin and vimentin in malignant rhabdoid tumor: three-dimensional imaging with confocal laser scanning microscopy and double immunofluorescence.

Oshiro Y., Oda Y., Ohta S., Furue M., Tsuneyoshi M.

Mod. Pathol. 14:854-861(2001).

Alteration of hSNF5/INI1/BAF47 detected in rhabdoid cell lines and primary rhabdomyosarcomas but not Wilms' tumors.

DeCristofaro M.F., Betz B.L., Wang W.-D., Weissman B.E.

Oncogene 18:7559-7565(1999).

Cloning and characterization of a novel Rab-family gene, Rab36, within the region at 22q11.2 that is homozygously deleted in malignant rhabdoid tumors.

Nakamura Y., Inazawa J.

Biochem. Biophys. Res. Commun. 254:594-600(1999).

Gene expression of malignant rhabdoid tumor cell lines by reverse transcriptase-polymerase chain reaction.

Suzuki A., Ohta S., Shimada M.

Diagn. Mol. Pathol. 6:326-332(1997).

Narrowing the critical region for a rhabdoid tumor locus in 22q11.";

Bell C.J.

Genes Chromosomes Cancer 16:94-105(1996).

Web Resources