JH-EsoAd1Homo sapiens (Human)Cancer cell line

Also known as: Johns Hopkins-Esophageal Adenocarcinoma 1, EsoAd1, JHESOAD1, JHesoAD1, JHEsoAD1

AI Summary

No AI-generated summary available for this cell line.

Basic Information

Database IDCVCL_8098
SpeciesHomo sapiens (Human)
Tissue SourceEsophagus[UBERON:UBERON_0001043]

Donor Information

Age66
Age CategoryAdult
SexMale

Disease Information

DiseaseAdenocarcinoma of the esophagus
LineageEsophagus/Stomach
SubtypeEsophageal Adenocarcinoma
OncoTree CodeESCA

DepMap Information

Source TypeAcademic lab
Source IDACH-000216_source

Known Sequence Variations

TypeGene/ProteinDescriptionZygosityNoteSource
MutationSimpleTP53p.Gly266Glu (c.797G>A)Unspecified-PubMed=21173094

Haplotype Information (STR Profile)

Short Tandem Repeat (STR) profile for cell line authentication.

Amelogenin
X
CSF1PO
10
D13S317
11
D16S539
10,12
D18S51
12
D21S11
30
D3S1358
16
D5S818
11
D7S820
10,12
D8S1179
10
FGA
24
Penta D
14
Penta E
11
TH01
6,7
TPOX
8,9
vWA
18,19
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines

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Publications

Next-generation characterization of the Cancer Cell Line Encyclopedia.

Sellers W.R.

Nature 569:503-508(2019).

An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.

Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.

Cancer Res. 79:1263-1273(2019).

Whole-genome sequencing of nine esophageal adenocarcinoma cell lines.";

Lynch A.G., Edwards P.A.W., Fitzgerald R.C.

F1000Research 5:1336.1-1336.12(2016).

Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies.

Golub T.R., Root D.E., Hahn W.C.

Sci. Data 1:140035-140035(2014).

Translational research on esophageal adenocarcinoma: from cell line to clinic.

Boonstra J.J., Tilanus H.W., Dinjens W.N.M.

Dis. Esophagus 28:90-96(2015).

Verification and unmasking of widely used human esophageal adenocarcinoma cell lines.

Shimada Y., van Dekken H., Tilanus H.W., Dinjens W.N.M.

J. Natl. Cancer Inst. 102:271-274(2010).

Cellular biometrics in the postgenomics era.";

Stairs D.B., Ohashi S., Nakagawa H.

Cancer Biol. Ther. 7:1756-1757(2008).

Establishment and characterization of a bona fide Barrett esophagus-associated adenocarcinoma cell line.

Forastiere A.A., Wu T.-T., Montgomery E.A., Eshleman J.R., Maitra A.

Cancer Biol. Ther. 7:1753-1755(2008).