L3.3Homo sapiens (Human)Cancer cell line
Also known as: L33
AI Summary
No AI-generated summary available for this cell line.
Basic Information
| Database ID | CVCL_8147 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Celiac axis lymph node[UBERON:UBERON_0002508] |
Donor Information
| Age | 77 |
|---|---|
| Age Category | Adult |
| Sex | Female |
Disease Information
| Disease | Squamous cell carcinoma of pancreas |
|---|---|
| Lineage | Pancreas |
| Subtype | Adenosquamous Carcinoma of the Pancreas |
| OncoTree Code | PAASC |
DepMap Information
| Source Type | Academic lab |
|---|---|
| Source ID | ACH-000685_source |
Known Sequence Variations
| Type | Gene/Protein | Description | Zygosity | Note | Source |
|---|---|---|---|---|---|
| MutationSimple | KRAS | p.Gly12Asp (c.35G>A) | Unspecified | - | PubMed=29786757 |
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines
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Publications
Quantitative proteomics of the Cancer Cell Line Encyclopedia.";
Sellers W.R., Gygi S.P.
Cell 180:387-402.e16(2020).
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Sellers W.R.
Nature 569:503-508(2019).
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
Cancer Res. 79:1263-1273(2019).
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
Loewer M., Sahin U., Castle J.C.
Genome Med. 7:118.1-118.7(2015).
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies.
Golub T.R., Root D.E., Hahn W.C.
Sci. Data 1:140035-140035(2014).
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
Nature 483:603-607(2012).
The metastatic potential of human pancreatic cell lines in the liver of nude mice correlates well with cathepsin B activity.
Tzanakakis G.N., Margioris A.N., Tsatsakis A.M., Vezeridis M.P.
Int. J. Gastrointest. Cancer 34:27-38(2003).