HTMMTHomo sapiens (Human)Cancer cell line
AI Summary
No AI-generated summary available for this cell line.
Basic Information
| Database ID | CVCL_8721 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Uterus[UBERON:UBERON_0000995] |
Donor Information
| Age | 66 |
|---|---|
| Age Category | Adult |
| Sex | Female |
Disease Information
| Disease | Carcinosarcoma of the corpus uteri |
|---|---|
| Lineage | Uterus |
| Subtype | Uterine Carcinosarcoma/Uterine Malignant Mixed Mullerian Tumor |
| OncoTree Code | UCS |
DepMap Information
| Source Type | RIKEN |
|---|---|
| Source ID | ACH-002046_source |
Known Sequence Variations
| Type | Gene/Protein | Description | Zygosity | Note | Source |
|---|---|---|---|---|---|
| MutationSimple | TP53 | p.Arg273His (c.818G>A) | Homozygous | - | Unknown, PubMed=16264262 |
| MutationSimple | PTEN | p.Ter404Leuext*8 (c.1211G>T) | Homozygous | - | Unknown, Unknown |
| MutationSimple | PTEN | p.Arg130Gly (c.388C>G) | Homozygous | - | Unknown, Unknown, PubMed=28273451 |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Amelogenin
X
CSF1PO
12
D13S317
10,13
D16S539
10,11
D5S818
11,12
D7S820
10
TH01
8,9
TPOX
8,11
vWA
19
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines
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Publications
Histogenesis of carcinosarcoma and establishment of leiomyosarcoma cell line (HTMMT) derived from human uterine carcinosarcoma.
Ishiwata I., Ishikawa H.
Hum. Cell 17:131-137(2004).
Effects of feeder cells (human cancer cell lines) on the development of mouse embryos by co-culture.
Ishikawa H.
Hum. Cell 10:237-246(1997).