YN-1Homo sapiens (Human)Cancer cell line
AI Summary
No AI-generated summary available for this cell line.
Basic Information
| Database ID | CVCL_8775 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Peripheral blood[UBERON:UBERON_0000178] |
Disease Information
| Disease | Chronic myeloid leukemia |
|---|
DepMap Information
Known Sequence Variations
| Type | Gene/Protein | Description | Zygosity | Note | Source |
|---|---|---|---|---|---|
| Gene fusion | ABL1 | BCR-ABL1, BCR-ABL | - | BCR exon 1 fused to ABL1 exon 2 | PubMed=10576511, PubMed=10071072, PubMed=8751477 |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Amelogenin
X
CSF1PO
11,12
D13S317
11,12
D16S539
11,13
D5S818
9,10
D7S820
12
TH01
9.3,10
TPOX
8,11
vWA
16,18
Publications
Leukemia cell lines: in vitro models for the study of Philadelphia chromosome-positive leukemia.
Drexler H.G., MacLeod R.A.F., Uphoff C.C.
Leuk. Res. 23:207-215(1999).
Cell surface c-kit receptors in human leukemia cell lines and pediatric leukemia: selective preservation of c-kit expression on megakaryoblastic cell lines during adaptation to in vitro culture.
Imaizumi M., Endo M., Takano N., Konno T.
Leukemia 10:102-105(1996).
Two chronic myelogenous leukaemia cell lines which represent different stages of erythroid differentiation.
Furuyama K., Kameoka J., Okuda M., Hayashi N., Yamamoto M., Abe K.
Br. J. Haematol. 85:653-662(1993).
Ultrastructural features of a human erythroid cell line (YN-1).";
Endo K., Tamahashi N.
Rinsho Ketsueki 28:667-677(1987).
The leukemia-lymphoma cell line factsbook.";
Drexler H.G.
(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001).