GSSHomo sapiens (Human)Cancer cell line
AI Summary
No AI-generated summary available for this cell line.
Basic Information
| Database ID | CVCL_8876 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Liver[UBERON:UBERON_0002107] |
Donor Information
| Age | 75 |
|---|---|
| Age Category | Adult |
| Sex | Male |
Disease Information
| Disease | Gastric carcinoma |
|---|---|
| Lineage | Esophagus/Stomach |
| Subtype | Stomach Adenocarcinoma |
| OncoTree Code | STAD |
DepMap Information
| Source Type | RIKEN |
|---|---|
| Source ID | ACH-000746_source |
Known Sequence Variations
| Type | Gene/Protein | Description | Zygosity | Note | Source |
|---|---|---|---|---|---|
| MutationSimple | TP53 | p.Leu194Arg (c.581T>G) | Unspecified | - | PubMed=20575032 |
| MutationSimple | CDKN2A | p.Asp84Asn (c.250G>A) (p.Arg98Gln, c.293G>A) | Homozygous | - | PubMed=31541927 |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Amelogenin
X
CSF1PO
9
D13S317
8
D16S539
12
D5S818
12,13
D7S820
11
TH01
7
TPOX
8
vWA
14
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines
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Publications
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Sellers W.R.
Nature 569:503-508(2019).
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
Cancer Res. 79:1263-1273(2019).
A compensatory role of NF-kappaB to p53 in response to 5-FU-based chemotherapy for gastric cancer cell lines.
Sato K., Iwaya T., Koeda K., Wakabayashi G.
PLoS ONE 9:E90155-E90155(2014).