HEY A8Homo sapiens (Human)Cancer cell line
Also known as: Heya8, HeyA8, HEYA8, Hey A8, Hey-A8, HEY-A8
No AI-generated summary available for this cell line.
Basic Information
| Database ID | CVCL_8878 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Ovary[UBERON:UBERON_0000992] |
Donor Information
| Age Category | Unknown |
|---|---|
| Sex | Female |
Disease Information
| Disease | High grade ovarian serous adenocarcinoma |
|---|---|
| Lineage | Ovary/Fallopian Tube |
| Subtype | High-Grade Serous Ovarian Cancer |
| OncoTree Code | HGSOC |
DepMap Information
| Source Type | Academic lab |
|---|---|
| Source ID | ACH-000542_source |
Known Sequence Variations
| Type | Gene/Protein | Description | Zygosity | Note | Source |
|---|---|---|---|---|---|
| MutationSimple | KRAS | p.Gly12Asp (c.35G>A) | Unspecified | - | PubMed=29786757 |
| MutationSimple | BRAF | p.Gly464Glu (c.1391G>A) | Unspecified | - | PubMed=12068308 |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
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Publications
Quantitative proteomics of the Cancer Cell Line Encyclopedia.";
Sellers W.R., Gygi S.P.
Cell 180:387-402.e16(2020).
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Sellers W.R.
Nature 569:503-508(2019).
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
Cancer Res. 79:1263-1273(2019).
Characterization of human cancer cell lines by reverse-phase protein arrays.
Liang H.
Cancer Cell 31:225-239(2017).
Integrative proteomic profiling of ovarian cancer cell lines reveals precursor cell associated proteins and functional status.
Tyanova S., Montag A., Lastra R.R., Lengyel E., Mann M.
Nat. Commun. 7:12645.1-12645.14(2016).
Characterization of ovarian cancer cell lines as in vivo models for preclinical studies.
Noonan A.M., Annunziata C.M.
Gynecol. Oncol. 142:332-340(2016).
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies.
Golub T.R., Root D.E., Hahn W.C.
Sci. Data 1:140035-140035(2014).
Evaluating cell lines as tumour models by comparison of genomic profiles.
Domcke S., Sinha R., Levine D.A., Sander C., Schultz N.
Nat. Commun. 4:2126.1-2126.10(2013).
DNA profiling analysis of endometrial and ovarian cell lines reveals misidentification, redundancy and contamination.
Lessey B.A., Jordan V.C., Bradford A.P.
Gynecol. Oncol. 127:241-248(2012).
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
Nature 483:603-607(2012).