YD-15Homo sapiens (Human)Cancer cell line

Also known as: YD15

AI Summary

No AI-generated summary available for this cell line.

Basic Information

Database IDCVCL_8930
SpeciesHomo sapiens (Human)
Tissue SourceOral cavity, tongue[UBERON:UBERON_0001723]

Donor Information

Age39
Age CategoryAdult
SexMale
Raceasian

Disease Information

DiseaseSquamous cell carcinoma of the oral tongue
LineageHead and Neck
SubtypeOral Cavity Squamous Cell Carcinoma
OncoTree CodeOCSC

DepMap Information

Source TypeKCLB
Source IDACH-000836_source

Known Sequence Variations

TypeGene/ProteinDescriptionZygosityNoteSource
MutationSimpleTP53p.Glu258Ala (c.773A>C)Unspecified-PubMed=16264262

Haplotype Information (STR Profile)

Short Tandem Repeat (STR) profile for cell line authentication.

Amelogenin
X,Y
CSF1PO
10,12
D13S317
11,12
D16S539
9,12
D18S51
14
D21S11
30,31.2
D3S1358
15
D5S818
12
D7S820
12,13
D8S1179
15
FGA
23
Penta D
9
Penta E
14,19
TH01
6,9
TPOX
9
vWA
15
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines

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Publications

Next-generation characterization of the Cancer Cell Line Encyclopedia.

Sellers W.R.

Nature 569:503-508(2019).

An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.

Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.

Cancer Res. 79:1263-1273(2019).

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.

Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.

Nature 483:603-607(2012).

Inhibition of myeloid cell leukemia-1 by tolfenamic acid induces apoptosis in mucoepidermoid carcinoma.

Choi K.-H., Shim J.-H., Huong L.D., Cho N.-P., Cho S.-D.

Oral Dis. 17:469-475(2011).

Characterization of newly established oral cancer cell lines derived from six squamous cell carcinoma and two mucoepidermoid carcinoma cells.

Yook J.-I.

Exp. Mol. Med. 37:379-390(2005).