YJHomo sapiens (Human)Cancer cell line
AI Summary
No AI-generated summary available for this cell line.
Basic Information
| Database ID | CVCL_8931 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Peripheral blood[UBERON:UBERON_0000178] |
Disease Information
| Disease | Acute myeloid leukemia |
|---|
DepMap Information
Known Sequence Variations
| Type | Gene/Protein | Description | Zygosity | Note | Source |
|---|---|---|---|---|---|
| MutationSimple | NRAS | p.Gln61Leu (c.182A>T) | Unspecified | - | PubMed=26214590 |
| MutationSimple | CDKN2A | p.Arg80Ter (c.238C>T) (p.Pro94Leu, c.281C>T) | Homozygous | - | from parent cell line HL-60 |
| Gene deletion | TP53 | - | Homozygous | 2 out of 3 copies | from parent cell line HL-60 |
Publications
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Freshney R.I.
Int. J. Cancer 127:1-8(2010).
Many are called MDS cell lines: one is chosen.";
Drexler H.G., Dirks W.G., MacLeod R.A.F.
Leuk. Res. 33:1011-1016(2009).
False leukemia-lymphoma cell lines: an update on over 500 cell lines.
Drexler H.G., Dirks W.G., Matsuo Y., MacLeod R.A.F.
Leukemia 17:416-426(2003).