ZK-58Homo sapiens (Human)Cancer cell line
Also known as: HOS 58, ZK58
AI Summary
No AI-generated summary available for this cell line.
Basic Information
| Database ID | CVCL_9920 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Bone, leg[UBERON:UBERON_0005893] |
Disease Information
| Disease | Osteosarcoma |
|---|
DepMap Information
Known Sequence Variations
| Type | Gene/Protein | Description | Zygosity | Note | Source |
|---|---|---|---|---|---|
| MutationNone reported | TP53 | - | - | - | PubMed=19787792 |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Amelogenin
X,Y
D16S539
11
D18S51
15,18
D19S433
12,14
D21S11
29,30.2
D2S1338
25
D3S1358
16
D5S818
11
D8S1179
13,14
FGA
24
SE33
24.2
TH01
6
TPOX
8
vWA
17,18
Publications
Integrative analysis reveals relationships of genetic and epigenetic alterations in osteosarcoma.
Myklebost O., Meza-Zepeda L.A.
PLoS ONE 7:E48262-E48262(2012).
Functional characterization of osteosarcoma cell lines provides representative models to study the human disease.
Hogendoorn P.C.W., Llombart-Bosch A., Cleton-Jansen A.-M.
Lab. Invest. 91:1195-1205(2011).
Molecular characterization of commonly used cell lines for bone tumor research: a trans-European EuroBoNet effort.
Buerger H., Aigner T., Gabbert H.E., Poremba C.
Genes Chromosomes Cancer 49:40-51(2010).
Expression profiling of t(12;22) positive clear cell sarcoma of soft tissue cell lines reveals characteristic up-regulation of potential new marker genes including ERBB3.
Gabbert H.E., Poremba C.
Cancer Res. 64:3395-3405(2004).
Chromosomal alterations in osteosarcoma cell lines revealed by comparative genomic hybridization and multicolor karyotyping.
Poremba C.
Cancer Genet. Cytogenet. 140:145-152(2003).