YCUB-5Homo sapiens (Human)Cancer cell line
Also known as: Yokohama City University BCP-ALL-5, YcuB5, YCUB5
AI Summary
No AI-generated summary available for this cell line.
Basic Information
| Database ID | CVCL_A085 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Bone marrow[UBERON:UBERON_0002371] |
Disease Information
| Disease | Precursor B-cell acute lymphoblastic leukemia |
|---|
DepMap Information
Known Sequence Variations
| Type | Gene/Protein | Description | Zygosity | Note | Source |
|---|---|---|---|---|---|
| MutationSimple | KRAS | p.Gly12Asp (c.35G>A) | Unspecified | - | PubMed=29786757 |
| MutationSimple | JAK2 | p.Arg683Ile (c.2048G>T) | Unspecified | - | PubMed=29786757 |
| Gene fusion | CRLF2 | P2RY8-CRLF2 | - | P2RY8 exon 1 fused to CRLF2 exon 1 | PubMed=29786757 |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Amelogenin
X,Y
CSF1PO
10,11
D13S317
8
D16S539
9,11
D18S51
13,15
D19S433
12
D21S11
30,30.2
D2S1338
18,23
D3S1358
15
D5S818
9,10
D7S820
9,11
D8S1179
14,16
FGA
20,21
Penta D
9,14
Penta E
11,17
TH01
6,9
TPOX
8,12
vWA
16
Publications
Glucocorticoid receptor gene mutations confer glucocorticoid resistance in B-cell precursor acute lymphoblastic leukemia.
Minegishi M., Iwamoto S., Sugita K., Inukai T.
J. Steroid Biochem. Mol. Biol. 218:106068.1-106068.12(2022).
Copy number abnormality of acute lymphoblastic leukemia cell lines based on their genetic subtypes.
Sugita K., Hosoi H.
Int. J. Hematol. 108:312-318(2018).