YCUB-6Homo sapiens (Human)Cancer cell line
Also known as: Yokohama City University BCP-ALL-6, YcuB6, YCUB6
AI Summary
No AI-generated summary available for this cell line.
Basic Information
| Database ID | CVCL_A087 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Peripheral blood[UBERON:UBERON_0000178] |
Disease Information
| Disease | B-lymphoblastic leukemia/lymphoma with t(1;19)(q23;p13.3) |
|---|
DepMap Information
Known Sequence Variations
| Type | Gene/Protein | Description | Zygosity | Note | Source |
|---|---|---|---|---|---|
| Gene fusion | PBX1 | TCF3-PBX1, E2A-PBX1 | - | - | PubMed=29786757 |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Amelogenin
X,Y
CSF1PO
10,13
D13S317
8,9
D16S539
9,10
D18S51
14,16
D19S433
14,16
D21S11
29,32.2
D2S1338
20,24
D3S1358
12,17
D5S818
13,14
D7S820
11
D8S1179
14
FGA
22,24
Penta D
12,13
Penta E
8,10
TH01
7,9
TPOX
8,9
vWA
16,19
Publications
Glucocorticoid receptor gene mutations confer glucocorticoid resistance in B-cell precursor acute lymphoblastic leukemia.
Minegishi M., Iwamoto S., Sugita K., Inukai T.
J. Steroid Biochem. Mol. Biol. 218:106068.1-106068.12(2022).
Aurora B kinase as a therapeutic target in acute lymphoblastic leukemia.
Hamanoue S., Shiomi M., Goto S.
Cancer Chemother. Pharmacol. 85:773-783(2020).
Copy number abnormality of acute lymphoblastic leukemia cell lines based on their genetic subtypes.
Sugita K., Hosoi H.
Int. J. Hematol. 108:312-318(2018).