ICC12Homo sapiens (Human)Cancer cell line

AI Summary

No AI-generated summary available for this cell line.

Basic Information

Database IDCVCL_A1VC
SpeciesHomo sapiens (Human)
Tissue SourcePeritoneum[UBERON:UBERON_0002358]

Donor Information

Age CategoryUnknown
SexUnknown

Disease Information

DiseaseCholangiocarcinoma
LineageBiliary Tract
SubtypeIntrahepatic Cholangiocarcinoma
OncoTree CodeIHCH

DepMap Information

Source TypeAcademic lab
Source IDACH-001838_source

Known Sequence Variations

TypeGene/ProteinDescriptionZygosityNoteSource
MutationSimpleTP53p.Pro190Leu (c.569C>T)Hemizygous-from parent cell line VACO 8
MutationSimpleBRAFp.Val600Glu (c.1799T>A)Unspecified-PubMed=26214590

Haplotype Information (STR Profile)

Short Tandem Repeat (STR) profile for cell line authentication.

Amelogenin
X
CSF1PO
12
D13S317
10,14
D16S539
9
D18S51
12,18,19
D21S11
31.2
D3S1358
14,15
D5S818
11,13
D7S820
11
D8S1179
13,14
FGA
20,21
Penta D
12,14
Penta E
12
TH01
8
TPOX
8
vWA
15,18
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines

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Publications

Generation of a biliary tract cancer cell line atlas reveals molecular subtypes and therapeutic targets.

Vazquez F., Getz G., Bardeesy N.M.

bioRxiv 2024:07.04.601970-07.04.601970(2024).