ICC13-7Homo sapiens (Human)Cancer cell line

Also known as: ICC137

AI Summary

No AI-generated summary available for this cell line.

Basic Information

Database IDCVCL_A1VD
SpeciesHomo sapiens (Human)
Tissue SourceLiver[UBERON:UBERON_0002107]

Donor Information

Age CategoryUnknown
SexUnknown

Disease Information

DiseaseCholangiocarcinoma
LineageBiliary Tract
SubtypeIntrahepatic Cholangiocarcinoma
OncoTree CodeIHCH

DepMap Information

Source TypeAcademic lab
Source IDACH-001839_source

Known Sequence Variations

TypeGene/ProteinDescriptionZygosityNoteSource
Gene fusionFGFR2FGFR2-OPTN-In frame. FGFR2 exon 17 fused to OPTN exon 9PubMed=31109923

Haplotype Information (STR Profile)

Short Tandem Repeat (STR) profile for cell line authentication.

Amelogenin
X
CSF1PO
10,12
D13S317
10
D16S539
11
D18S51
13,14
D21S11
32.2
D3S1358
18
D5S818
10,11
D7S820
8,9
D8S1179
12,13
FGA
22
Penta D
9
Penta E
5,7
TH01
6,7
TPOX
11
vWA
15,18
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines

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Publications

Generation of a biliary tract cancer cell line atlas reveals molecular subtypes and therapeutic targets.

Vazquez F., Getz G., Bardeesy N.M.

bioRxiv 2024:07.04.601970-07.04.601970(2024).

TAS-120 overcomes resistance to ATP-competitive FGFR inhibitors in patients with FGFR2 fusion-positive intrahepatic cholangiocarcinoma.

Zhu A.X.-X., Corcoran R.B., Bardeesy N.M.

Cancer Discov. 9:1064-1079(2019).