ICC6Homo sapiens (Human)Cancer cell line

AI Summary

No AI-generated summary available for this cell line.

Basic Information

Database IDCVCL_A1VF
SpeciesHomo sapiens (Human)
Tissue SourceLiver[UBERON:UBERON_0002107]

Donor Information

Age CategoryUnknown
SexUnknown

Disease Information

DiseaseCholangiocarcinoma
LineageBiliary Tract
SubtypeIntrahepatic Cholangiocarcinoma
OncoTree CodeIHCH

DepMap Information

Source TypeAcademic lab
Source IDACH-001846_source

Known Sequence Variations

TypeGene/ProteinDescriptionZygosityNoteSource
MutationSimpleTP53p.Cys135Phe (c.404G>T)Heterozygous-PubMed=22170099, PubMed=19147553, PubMed=16142320
MutationSimpleTP53p.Lys132Thr (c.395A>C)Heterozygous-Unknown, Unknown

Haplotype Information (STR Profile)

Short Tandem Repeat (STR) profile for cell line authentication.

Amelogenin
X
CSF1PO
12,13
D13S317
12
D16S539
11,12
D18S51
13
D21S11
30
D3S1358
14,15
D5S818
11,12
D7S820
10
D8S1179
13
FGA
20,21
Penta D
15
Penta E
12,19
TH01
6,9.3
TPOX
8
vWA
14,20
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines

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Publications

Generation of a biliary tract cancer cell line atlas reveals molecular subtypes and therapeutic targets.

Vazquez F., Getz G., Bardeesy N.M.

bioRxiv 2024:07.04.601970-07.04.601970(2024).