WM1799Homo sapiens (Human)Cancer cell line
Also known as: WM 1799, WM-1799
AI Summary
No AI-generated summary available for this cell line.
Basic Information
| Database ID | CVCL_A341 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Not specified |
Donor Information
| Age Category | Unknown |
|---|---|
| Sex | Male |
Disease Information
| Disease | Melanoma |
|---|---|
| Lineage | Skin |
| Subtype | Melanoma |
| OncoTree Code | MEL |
DepMap Information
| Source Type | Academic lab |
|---|---|
| Source ID | ACH-000661_source |
Known Sequence Variations
| Type | Gene/Protein | Description | Zygosity | Note | Source |
|---|---|---|---|---|---|
| MutationSimple | BRAF | p.Val600Glu (c.1799T>A) | Unspecified | - | PubMed=26214590 |
| Gene deletion | PTEN | - | Hemizygous | - | Wistar |
| Gene deletion | CDKN2A | - | Homozygous | Possible | PubMed=26870271 |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Amelogenin
X,Y
CSF1PO
11
D13S317
11,12
D16S539
11
D18S51
13,16
D19S433
16,16.2
D21S11
30
D2S1338
18
D3S1358
14,15
D5S818
11
D7S820
9
D8S1179
12,14
FGA
19,24
TH01
9.3
TPOX
8
vWA
14,17
Gene Expression Profile
Gene expression levels and statistical distribution
Loading cohorts...
Full DepMap dataset with combined data across cell lines
Loading gene expression data...
Publications
Quantitative proteomics of the Cancer Cell Line Encyclopedia.";
Sellers W.R., Gygi S.P.
Cell 180:387-402.e16(2020).
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Sellers W.R.
Nature 569:503-508(2019).
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
Cancer Res. 79:1263-1273(2019).
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
Loewer M., Sahin U., Castle J.C.
Genome Med. 7:118.1-118.7(2015).
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
Nature 483:603-607(2012).
Identification of a novel subgroup of melanomas with KIT/cyclin-dependent kinase-4 overexpression.
Nathanson K.L.
Cancer Res. 68:5743-5752(2008).
Metastatic potential of melanomas defined by specific gene expression profiles with no BRAF signature.
Dummer R.
Pigment Cell Res. 19:290-302(2006).