ZR-75-1 Tam2Homo sapiens (Human)Cancer cell line

AI Summary

No AI-generated summary available for this cell line.

Basic Information

Database IDCVCL_A4AM
SpeciesHomo sapiens (Human)
Tissue SourceAscites[UBERON:UBERON_0007795]

Disease Information

DiseaseInvasive breast carcinoma of no special type

DepMap Information

Known Sequence Variations

TypeGene/ProteinDescriptionZygosityNoteSource
MutationSimplePTENp.Leu108Arg (c.323T>G)Homozygous-from parent cell line ZR-75-1
MutationSimpleHRASp.Glu162Lys (c.484G>A)Homozygous-from parent cell line ZR-75-1

Publications

Systematic drug screening reveals specific vulnerabilities and co-resistance patterns in endocrine-resistant breast cancer.

Eldfors S., Bruck O., Aittokallio T., Kallioniemi O.-P.

BMC Cancer 16:378.1-378.17(2016).