YS9;22Homo sapiens (Human)Cancer cell line
Also known as: YS 9:22, YS9-22, YS9:22
AI Summary
No AI-generated summary available for this cell line.
Basic Information
| Database ID | CVCL_A743 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Peripheral blood[UBERON:UBERON_0000178] |
Disease Information
| Disease | Chronic myeloid leukemia |
|---|
DepMap Information
Known Sequence Variations
| Type | Gene/Protein | Description | Zygosity | Note | Source |
|---|---|---|---|---|---|
| Gene fusion | ABL1 | BCR-ABL1, BCR-ABL | - | BCR exon 1 fused to ABL1 exon 2 | PubMed=10576511, PubMed=10071072, PubMed=8751477 |
Publications
JAK2 V617F tyrosine kinase mutation in cell lines derived from myeloproliferative disorders.
Quentmeier H., MacLeod R.A.F., Zaborski M., Drexler H.G.
Leukemia 20:471-476(2006).
Corrigendum to: Frequent microsatellite instability and BAX mutations in T cell acute lymphoblastic leukemia cell lines Leukemia Research 24 (2000), 255-262.
Inoue K., Kohno T., Takakura S., Hayashi Y., Mizoguchi H., Yokota J.
Leuk. Res. 25:275-278(2001).
Frequent microsatellite instability and BAX mutations in T cell acute lymphoblastic leukemia cell lines.
Inoue K., Kohno T., Takakura S., Hayashi Y., Mizoguchi H., Yokota J.
Leuk. Res. 24:255-262(2000).
ABL-BCR expression in BCR-ABL-positive human leukemia cell lines.";
Uphoff C.C., Habig S., Fombonne S., Matsuo Y., Drexler H.G.
Leuk. Res. 23:1055-1060(1999).
Leukemia cell lines: in vitro models for the study of Philadelphia chromosome-positive leukemia.
Drexler H.G., MacLeod R.A.F., Uphoff C.C.
Leuk. Res. 23:207-215(1999).
EVI1 expression associated with a 3q26 anomaly in a leukemia cell line derived from the blast crisis of chronic myeloid leukemia.
Nakazawa S., Suzukawa K., Morishita K., Toyama K.
Leukemia 8:2169-2173(1994).
The leukemia-lymphoma cell line factsbook.";
Drexler H.G.
(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001).