YUMACHomo sapiens (Human)Cancer cell line
AI Summary
No AI-generated summary available for this cell line.
Basic Information
| Database ID | CVCL_A745 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Thigh, hypodermis[UBERON:UBERON_0002072] |
Disease Information
| Disease | Cutaneous melanoma |
|---|
DepMap Information
Known Sequence Variations
| Type | Gene/Protein | Description | Zygosity | Note | Source |
|---|---|---|---|---|---|
| MutationSimple | BRAF | p.Val600Lys (c.1798_1799delGTinsAA) | Heterozygous | - | from parent cell line YUSIT1 |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Amelogenin
X
CSF1PO
11,12
D13S317
10
D16S539
11
D18S51
16,17
D21S11
30
D3S1358
15
D5S818
12
D7S820
9
D8S1179
10,12
FGA
21
Penta D
12,13
Penta E
7,12
TH01
6
TPOX
12
vWA
17,19
Publications
Exome sequencing identifies recurrent mutations in NF1 and RASopathy genes in sun-exposed melanomas.
Schlessinger J., Lifton R.P., Halaban R.
Nat. Genet. 47:996-1002(2015).
Integrated analysis of tumor samples sheds light on tumor heterogeneity.
Kluger Y.
Yale J. Biol. Med. 85:347-361(2012).
Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma.
Lifton R.P., Schlessinger J., Boggon T.J., Halaban R.
Nat. Genet. 44:1006-1014(2012).
Detecting copy number status and uncovering subclonal markers in heterogeneous tumor biopsies.
Xu F., Li P.-N., Halaban R., Kluger Y.
BMC Genomics 12:230.1-230.14(2011).
MicroRNA signatures differentiate melanoma subtypes.";
Krauthammer M., Tuck D., Slack F.J., Weidhaas J.B.
Cell Cycle 10:1845-1852(2011).