SMS-CTRHomo sapiens (Human)Cancer cell line
Also known as: SMSCTR, SMS_CTR
AI Summary
No AI-generated summary available for this cell line.
Basic Information
| Database ID | CVCL_A770 |
|---|---|
| Species | Homo sapiens (Human) |
Donor Information
| Age | 1 |
|---|---|
| Age Category | Pediatric |
| Sex | Male |
Disease Information
| Disease | Embryonal rhabdomyosarcoma |
|---|---|
| Lineage | Soft Tissue |
| Subtype | Embryonal Rhabdomyosarcoma |
| OncoTree Code | ERMS |
DepMap Information
| Source Type | Academic lab |
|---|---|
| Source ID | ACH-001196_source |
Known Sequence Variations
| Type | Gene/Protein | Description | Zygosity | Note | Source |
|---|---|---|---|---|---|
| MutationSimple | HRAS | p.Gln61Lys (c.181C>A) | Unspecified | - | PubMed=26214590 |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Amelogenin
X,Y
CSF1PO
12
D13S317
11
D16S539
10,11
D18S51
13
D19S433
14
D21S11
29,31.2
D2S1338
24
D3S1358
17
D5S818
12
D7S820
8,11
D8S1179
10,12
FGA
21,22
TH01
6
TPOX
8,12
vWA
18,19
Gene Expression Profile
Gene expression levels and statistical distribution
Loading cohorts...
Full DepMap dataset with combined data across cell lines
Loading gene expression data...
Publications
Characterization of human cancer cell lines by reverse-phase protein arrays.
Liang H.
Cancer Cell 31:225-239(2017).
Human rhabdomyosarcoma cell lines for rhabdomyosarcoma research: utility and pitfalls.
Linardic C.M.
Front. Oncol. 3:183.1-183.12(2013).
Oncogene mutation profiling of pediatric solid tumors reveals significant subsets of embryonal rhabdomyosarcoma and neuroblastoma with mutated genes in growth signaling pathways.
Borsu L., Barr F.G., Ladanyi M.
Clin. Cancer Res. 18:748-757(2012).
Inhibition of the Notch-Hey1 axis blocks embryonal rhabdomyosarcoma tumorigenesis.
Belyea B.C., Naini S., Bentley R.C., Linardic C.M.
Clin. Cancer Res. 17:7324-7336(2011).
Fusion of a fork head domain gene to PAX3 in the solid tumour alveolar rhabdomyosarcoma.
Rauscher F.J. 3rd, Emanuel B.S., Rovera G., Barr F.G.
Nat. Genet. 5:230-235(1993).
In vitro purging of human rhabdomyosarcoma cells using 4-hydroperoxycyclophosphamide.
Ozkaynak M.F., Nolta J., Parkman R.
Cancer Res. 50:1455-1458(1990).