RMS-YMHomo sapiens (Human)Cancer cell line
Also known as: RMSYM
AI Summary
No AI-generated summary available for this cell line.
Basic Information
| Database ID | CVCL_A792 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Urachus[UBERON:UBERON_0002068] |
Donor Information
| Age | 2 |
|---|---|
| Age Category | Pediatric |
| Sex | Male |
Disease Information
| Disease | Embryonal rhabdomyosarcoma |
|---|---|
| Lineage | Soft Tissue |
| Subtype | Embryonal Rhabdomyosarcoma |
| OncoTree Code | ERMS |
DepMap Information
| Source Type | RIKEN |
|---|---|
| Source ID | ACH-002048_source |
Known Sequence Variations
| Type | Gene/Protein | Description | Zygosity | Note | Source |
|---|---|---|---|---|---|
| MutationSimple | BCOR | p.Arg1163Ter (c.3487C>T) | Homozygous | - | Unknown |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Amelogenin
X,Y
CSF1PO
11
D13S317
10,11
D16S539
11
D5S818
12,14
D7S820
10,11
TH01
9
TPOX
11
vWA
18
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines
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Publications
Human rhabdomyosarcoma cell lines for rhabdomyosarcoma research: utility and pitfalls.
Linardic C.M.
Front. Oncol. 3:183.1-183.12(2013).
Cetuximab promotes anticancer drug toxicity in rhabdomyosarcomas with EGFR amplification in vitro.
Kitagawa Y., Morikawa Y., Kuroda T.
Oncol. Rep. 30:1081-1086(2013).
Genomic imbalances in rhabdomyosarcoma cell lines affect expression of genes frequently altered in primary tumors: an approach to identify candidate genes involved in tumor development.
Pritchard-Jones K., Kool M., Shipley J.M.
Genes Chromosomes Cancer 48:455-467(2009).