BCK4Homo sapiens (Human)Cancer cell line

Also known as: BCK-4

AI Summary

No AI-generated summary available for this cell line.

Basic Information

Database IDCVCL_A9A5
SpeciesHomo sapiens (Human)
Tissue SourcePleural effusion[UBERON:UBERON_0000175]

Donor Information

Age65
Age CategoryAdult
SexFemale

Disease Information

DiseaseInvasive breast lobular carcinoma
LineageBreast
SubtypeBreast Invasive Lobular Carcinoma
OncoTree CodeILC

DepMap Information

Source TypeAcademic lab
Source IDACH-002921_source

Haplotype Information (STR Profile)

Short Tandem Repeat (STR) profile for cell line authentication.

Amelogenin
X
CSF1PO
11
D13S317
12,13
D16S539
13
D18S51
13,14
D21S11
30,30.2
D3S1358
14,15
D5S818
11,12
D7S820
9,11
D8S1179
12,16
FGA
21,24
Penta D
10,13
Penta E
7,13
TH01
7,9.3
TPOX
8,11
vWA
16
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines

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Publications

Mucin 2 (MUC2) modulates the aggressiveness of breast cancer.";

Astashchanka A., Shroka T.M., Jacobsen B.M.

Breast Cancer Res. Treat. 173:289-299(2019).

Comprehensive phenotypic characterization of human invasive lobular carcinoma cell lines in 2D and 3D cultures.

Jacobsen B.M., Tseng G.C.-C., Davidson N.E., Oesterreich S.

Cancer Res. 78:6209-6222(2018).

Estrogen induces c-Kit and an aggressive phenotype in a model of invasive lobular breast cancer.

Harrell J.C., Shroka T.M., Jacobsen B.M.

Oncogenesis 6:396.1-396.16(2017).

Cooperative dynamics of AR and ER activity in breast cancer.";

Richer J.K.

Mol. Cancer Res. 14:1054-1067(2016).

Lobular breast cancer: molecular basis, mouse and cellular models.";

Christgen M., Derksen P.W.B.

Breast Cancer Res. 17:16.1-16.9(2015).

Estrogen switches pure mucinous breast cancer to invasive lobular carcinoma with mucinous features.

Sollender G.E., Spillman M.A., Horwitz K.B., Jacobsen B.M.

Breast Cancer Res. Treat. 137:431-448(2013).