UPMD-2Homo sapiens (Human)Cancer cell line
Also known as: Uveal Primary Melanoma with Disomy-3 2, UPMD2
AI Summary
No AI-generated summary available for this cell line.
Basic Information
| Database ID | CVCL_C298 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Eye, uvea[UBERON:UBERON_0001768] |
Donor Information
| Age Category | Unknown |
|---|---|
| Sex | Female |
Disease Information
| Disease | Uveal melanoma |
|---|---|
| Lineage | Eye |
| Subtype | Uveal Melanoma |
| OncoTree Code | UM |
DepMap Information
| Source Type | QIMRB Berghofer |
|---|---|
| Source ID | ACH-002927_source |
Known Sequence Variations
| Type | Gene/Protein | Description | Zygosity | Note | Source |
|---|---|---|---|---|---|
| MutationSimple | GNA11 | p.Gln209Leu (c.626A>T) | Unspecified | - | PubMed=22236444 |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Amelogenin
X
CSF1PO
11
D13S317
11,12
D16S539
9,13
D3S1358
18
D5S818
11
D7S820
8
FGA
24,25
TH01
6,9.3
TPOX
8,11
vWA
17,18
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines
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Publications
Evidence of epidermal growth factor receptor expression in uveal melanoma: inhibition of epidermal growth factor-mediated signalling by gefitinib and cetuximab triggered antibody-dependent cellular cytotoxicity.
Salvi S., Truini M., Poggi A., Pfeffer U.
Eur. J. Cancer 49:3353-3365(2013).
Genetic and molecular characterization of uveal melanoma cell lines.
Bernatchez C., Wardell S., Bastian B.C., Woodman S.E.
Pigment Cell Melanoma Res. 25:182-187(2012).